ID A0A372JR55_9ACTN Unreviewed; 254 AA.
AC A0A372JR55;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Antibiotic biosynthesis monooxygenase {ECO:0000313|EMBL:RFU41838.1};
GN ORFNames=DZF91_09705 {ECO:0000313|EMBL:RFU41838.1};
OS Actinomadura logoneensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2293572 {ECO:0000313|EMBL:RFU41838.1, ECO:0000313|Proteomes:UP000261811};
RN [1] {ECO:0000313|EMBL:RFU41838.1, ECO:0000313|Proteomes:UP000261811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEAU-G17 {ECO:0000313|EMBL:RFU41838.1,
RC ECO:0000313|Proteomes:UP000261811};
RA Shi L.;
RT "Actinomadura jelena sp. nov., a novel Actinomycete isolated from soil in
RT Chad.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFU41838.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QURH01000182; RFU41838.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A372JR55; -.
DR OrthoDB; 9798157at2; -.
DR Proteomes; UP000261811; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd14775; TrHb2_O-like; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR007138; ABM_dom.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR001486; Hemoglobin_trunc.
DR Pfam; PF03992; ABM; 1.
DR Pfam; PF01152; Bac_globin; 1.
DR SUPFAM; SSF54909; Dimeric alpha+beta barrel; 1.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS51725; ABM; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|PIRSR:PIRSR601486-1};
KW Iron {ECO:0000256|PIRSR:PIRSR601486-1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR601486-1};
KW Monooxygenase {ECO:0000313|EMBL:RFU41838.1};
KW Oxidoreductase {ECO:0000313|EMBL:RFU41838.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000261811}.
FT DOMAIN 2..92
FT /note="ABM"
FT /evidence="ECO:0000259|PROSITE:PS51725"
FT BINDING 172
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="distal binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR601486-1"
SQ SEQUENCE 254 AA; 28763 MW; 091AE9512A97E1FB CRC64;
MIVEYIRYRI AGADADGFEA AYAGAAASLA AAPQCVDYEL SRCVDEPEWY VLRITWTSAA
AHLQEFRSGE HFAAFFAEIR PYVDRIEEMR HYEWTAVRGL GGSVPTMYEW AGGEEAFQRL
TEVFYGHVLK DDLIGPLFAH MDKDHPRYVA MWLAEVFGGP ERYSAERGGY HHMVRQHLGK
AISEPQRRRW VNLLMDAADD VGLPDDPEFR AAFASYIEWG TRIAHTNSQP DATPPLEAPM
PHWGWGVAPP YIPS
//
