ID   A0A372JWA1_9ACTN        Unreviewed;       539 AA.
AC   A0A372JWA1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=CCA tRNA nucleotidyltransferase {ECO:0000313|EMBL:RFU43628.1};
DE            EC=2.7.7.72 {ECO:0000313|EMBL:RFU43628.1};
GN   ORFNames=DZF91_00155 {ECO:0000313|EMBL:RFU43628.1};
OS   Actinomadura logoneensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2293572 {ECO:0000313|EMBL:RFU43628.1, ECO:0000313|Proteomes:UP000261811};
RN   [1] {ECO:0000313|EMBL:RFU43628.1, ECO:0000313|Proteomes:UP000261811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-G17 {ECO:0000313|EMBL:RFU43628.1,
RC   ECO:0000313|Proteomes:UP000261811};
RA   Shi L.;
RT   "Actinomadura jelena sp. nov., a novel Actinomycete isolated from soil in
RT   Chad.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFU43628.1}.
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DR   EMBL; QURH01000005; RFU43628.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372JWA1; -.
DR   OrthoDB; 9805698at2; -.
DR   Proteomes; UP000261811; Unassembled WGS sequence.
DR   GO; GO:0004810; F:CCA tRNA nucleotidyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd05398; NT_ClassII-CCAase; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR002646; PolA_pol_head_dom.
DR   InterPro; IPR032828; PolyA_RNA-bd.
DR   InterPro; IPR014065; tRNA_adenylyltransferase.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   NCBIfam; TIGR02692; tRNA_CCA_actino; 1.
DR   PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF01743; PolyA_pol; 1.
DR   Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:RFU43628.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261811};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RFU43628.1}.
FT   DOMAIN          267..433
FT                   /note="HD/PDEase"
FT                   /evidence="ECO:0000259|SMART:SM00471"
FT   REGION          483..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          400..427
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        519..539
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  59031 MW;  A927B45DE916726E CRC64;
     MAVPDPNAIP NAPDAGRAAI TELLSRVAPV AEDLAGRFAA AGHELALVGG PVRDALLRRP
     TKDVDLTTDA PPQRILEIID GWADAIWTIG IEFGTVGLRK DGHELEITTY RSETYDPKSR
     KPEVSYGTSL VEDLRRRDFA VNAMAVKLPA YEFVDPFGGL VDLGRGLLRT PGLPEDSFGD
     DPLRMLRAAR FASQLGFAVA PDVVAAMTEM ASRIGIVSAE RVRDELSKLL CGAHPREGLA
     LLVDTGLAAH VLPELPKLRL EIDEHHRHKD VYEHSLIVLE QAIAQEEGGP DLVLRLAALL
     HDIGKPKTRR FETGGRVSFH HHEVVGAKMA RKRLTELRYP KDVVGEVSRL VELHLRFHGY
     GTGEWTDSAV RRYVRDAGPL LSRLHKLTRA DCTTRNRRKA ERLRRTYDEL EVRIARLAEE
     EELASIRPEL DGNEIQEILG IRPGPIVGKA YKHLLELRLD RGPVGKGAAA EALRAWGAEH
     GVLPAGSPRT VPPEPAQPES PQTESPQTET PQAEPARADE AGKPGEHAAA ERAGSEDEG
//