ID A0A373LLL5_9FIRM Unreviewed; 578 AA.
AC A0A373LLL5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Phosphoglucomutase {ECO:0000256|ARBA:ARBA00039995};
DE AltName: Full=Alpha-phosphoglucomutase {ECO:0000256|ARBA:ARBA00041467};
DE AltName: Full=Glucose phosphomutase {ECO:0000256|ARBA:ARBA00041398};
GN ORFNames=DW006_08000 {ECO:0000313|EMBL:RGF50588.1};
OS Eubacterium sp. AF36-5BH.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=2293108 {ECO:0000313|EMBL:RGF50588.1, ECO:0000313|Proteomes:UP000262191};
RN [1] {ECO:0000313|EMBL:RGF50588.1, ECO:0000313|Proteomes:UP000262191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF36-5BH {ECO:0000313|EMBL:RGF50588.1,
RC ECO:0000313|Proteomes:UP000262191};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Glycolipid metabolism; diglucosyl-diacylglycerol biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005164}.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231, ECO:0000256|RuleBase:RU004326}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGF50588.1}.
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DR EMBL; QTVG01000006; RGF50588.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A373LLL5; -.
DR OrthoDB; 9806956at2; -.
DR Proteomes; UP000262191; Unassembled WGS sequence.
DR GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05799; PGM2; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR016066; A-D-PHexomutase_CS.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR PANTHER; PTHR45745:SF1; PHOSPHOGLUCOMUTASE 2A-RELATED; 1.
DR PANTHER; PTHR45745; PHOSPHOMANNOMUTASE 45A; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
DR PROSITE; PS00710; PGM_PMM; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|RuleBase:RU004326};
KW Metal-binding {ECO:0000256|RuleBase:RU004326};
KW Reference proteome {ECO:0000313|Proteomes:UP000262191}.
FT DOMAIN 43..179
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 207..312
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 326..452
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
SQ SEQUENCE 578 AA; 64701 MW; 4A6BE99A34152D73 CRC64;
MDYRELYNEW LTNPYFDDNT KKELEAIEND DKEIEDRFYK ELEFGTAGLR GVIGAGTNRM
NIYTVRKATQ GLANYIIKMH GEDKGVAIAY DSRHMSPEFA DEAALCLNAN GIKAYVFDSL
RPTPELSFAV RELKCIAGIN VTASHNPAEY NGYKVYWEDG AQITPPHDVG IMDAVAALKD
YNKVKTMDKD QAVADGLYIQ IGKEVDDKYI EILKTQVKNP DAIKEVQKDI KIVYTPLHGT
GNIPVRRVLK ELGFENVYVV KEQELPDGDF PTVGYPNPES AKAFELAVKL GNEVGADLLL
ATDPDADRLG VYVKGSKPGT YHILTGNMSG CLLAEYEISQ LKEKGQLPSD GAFIKSIVST
NLANDIAKYY NINLFEVLTG FKYIGEKMLD FEVNHTGTYV FGFEESYGCL IGTHARDKDA
IVASMALCEA AAYYKTKGMS LWDKMKEMYE RYGYWSDGVQ SIELKGKEGI EKIQNTLEKL
RENVPTTVDN YKVLSVRDYL ADTVTNMETG DVTTTGLPKS NVLYLDLSEC AWVCIRPSGT
EPKLKFYYGV KGENFDDSKA KLADLGSYMI NMVNEMLK
//
