ID   A0A373LNH4_9FIRM        Unreviewed;       479 AA.
AC   A0A373LNH4;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Peptidoglycan endopeptidase {ECO:0000313|EMBL:RGF51963.1};
GN   ORFNames=DW006_03925 {ECO:0000313|EMBL:RGF51963.1};
OS   Eubacterium sp. AF36-5BH.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=2293108 {ECO:0000313|EMBL:RGF51963.1, ECO:0000313|Proteomes:UP000262191};
RN   [1] {ECO:0000313|EMBL:RGF51963.1, ECO:0000313|Proteomes:UP000262191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF36-5BH {ECO:0000313|EMBL:RGF51963.1,
RC   ECO:0000313|Proteomes:UP000262191};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGF51963.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QTVG01000003; RGF51963.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A373LNH4; -.
DR   Proteomes; UP000262191; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR003646; SH3-like_bac-type.
DR   PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   SMART; SM00287; SH3b; 2.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262191};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        30..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          286..412
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   REGION          417..479
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        434..473
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  53802 MW;  71F83E3F09DBC9EE CRC64;
     MKLYKKWEVE IKRMNFIKEK INKLSFDKKT VIKAVGILVV FAVAIGTIVL IGHNGKTTSS
     KEVQTTTTQA EVAKTKKVTK TKKTKTKKKQ PLYGKKYKKL KIVRVYDDKS FEEIDDIDDD
     IAEVYKDKSM ASDEAGVALE GCVVKVVESG KEWTKIKSGK VEGYIESKYV VKGKEAKKVL
     LRTEHVIAKI KSENVAIRKD GNKKAASIGV AYKKTEYPIV EISKNEKWVK IKRSEAVTGW
     IPAGQMTLKV QKEKVYTSEE YDEMVDTQWT GGIVGYSLAE KDLPKKGEAR DLIKYASKFL
     GNRYVWGGTS LTRGADCSGF VQSVFRKFGR YLNRTAAEQA KNGSAVSLNK LKSGDLVFYH
     TDKRDKNRIS HVAIYIGNGK VIHSANRKVG MVISAVGSPC AARRILTAEN LKLKSKKEVE
     TKKAKKKKET KHKSKDKTKE EQTTKAQPET KNPETETKNT ESETTKEIET TIEENSSEI
//