ID   A0A373NFY3_9FIRM        Unreviewed;       339 AA.
AC   A0A373NFY3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Low specificity L-threonine aldolase {ECO:0000313|EMBL:RGF73396.1};
GN   ORFNames=DWZ38_12375 {ECO:0000313|EMBL:RGF73396.1};
OS   Ruminococcus sp. AF31-8BH.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=2293174 {ECO:0000313|EMBL:RGF73396.1, ECO:0000313|Proteomes:UP000262205};
RN   [1] {ECO:0000313|EMBL:RGF73396.1, ECO:0000313|Proteomes:UP000262205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF31-8BH {ECO:0000313|EMBL:RGF73396.1,
RC   ECO:0000313|Proteomes:UP000262205};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGF73396.1}.
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DR   EMBL; QTVN01000009; RGF73396.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A373NFY3; -.
DR   OrthoDB; 9774495at2; -.
DR   Proteomes; UP000262205; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   PANTHER; PTHR48097:SF5; LOW SPECIFICITY L-THREONINE ALDOLASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000262205}.
FT   DOMAIN          15..292
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   339 AA;  37933 MW;  473C777F8AF25DF4 CRC64;
     MLYFENDYCE GAHEAILKRL LETNMEKVPG YGQDPYCDQA KEKIKAACGC TDGEVYFLVG
     GTQTNAVVIA SMLNRYEGVL SAVTGHVNAH EAGAIEFTGH KVLPLPQKDG KISAADLKNY
     LETYYADGSY DHMVFPGMVY ISHPTEYGTL YTRQELEDIS GVCRKYEIPL FLDGARLGYG
     LVADTDVTLK DIAKYTDVFY IGGTKVGALC GEAVVFPKKT PKHFFTMIKQ QGALLAKGRL
     LGIQFDALFT DNLYLEISKN AIDTAAKLKS ALKEKNYQFF LDSPTNQIFV VLENQKMEEL
     GKKVKYGFWE KYDDNHTVVR FATSWATKME DIDALIEIL
//