ID   A0A374TF83_9BACT        Unreviewed;       344 AA.
AC   A0A374TF83;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Amino acid lyase {ECO:0000313|EMBL:RGK33623.1};
GN   ORFNames=DXD25_04075 {ECO:0000313|EMBL:RGK33623.1};
OS   Prevotella sp. TF12-30.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=2292365 {ECO:0000313|EMBL:RGK33623.1, ECO:0000313|Proteomes:UP000262185};
RN   [1] {ECO:0000313|EMBL:RGK33623.1, ECO:0000313|Proteomes:UP000262185}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TF12-30 {ECO:0000313|EMBL:RGK33623.1,
RC   ECO:0000313|Proteomes:UP000262185};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGK33623.1}.
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DR   EMBL; QSQJ01000006; RGK33623.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A374TF83; -.
DR   Proteomes; UP000262185; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   PANTHER; PTHR48097:SF5; LOW SPECIFICITY L-THREONINE ALDOLASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:RGK33623.1}.
FT   DOMAIN          5..291
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   344 AA;  38485 MW;  D0B5F52F94F3CDE7 CRC64;
     MISFESDYNN GMLPEILEAL GKTNREKTSG YGFDSYSESA KEKIRKAVDN ENAEVFFLIG
     GTQTNTTVID SVLRGCEGVI CVETGHIEVH ESGAVEAFGH KVITLPGENS KLTSSTLSAY
     MDTFLADETH PHMVQPGMVY ISMPTEFGMV YTMEELTALY TTCQKYNLRL FIDGARLGYG
     LVSEACDYDL PFLANHCDVF YIGGTKVGAM MGEAVVFSGM KAPKYFFTNI KRHGALLAKG
     RMLGIQFDTL FTDNLYFKIS RHAIAMATRI RSIFQKHGIA IAYDSPTNQQ FVVLSPSLYD
     ALSKKVAFEI WERKSDTEII CRFVTSWATK EEELEELEHI LQTL
//