ID A0A374TFF9_9BACT Unreviewed; 873 AA.
AC A0A374TFF9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=DNA translocase FtsK {ECO:0000313|EMBL:RGK34954.1};
GN ORFNames=DXD25_03205 {ECO:0000313|EMBL:RGK34954.1};
OS Prevotella sp. TF12-30.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=2292365 {ECO:0000313|EMBL:RGK34954.1, ECO:0000313|Proteomes:UP000262185};
RN [1] {ECO:0000313|EMBL:RGK34954.1, ECO:0000313|Proteomes:UP000262185}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF12-30 {ECO:0000313|EMBL:RGK34954.1,
RC ECO:0000313|Proteomes:UP000262185};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGK34954.1}.
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DR EMBL; QSQJ01000004; RGK34954.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A374TFF9; -.
DR Proteomes; UP000262185; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 515..720
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 240..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 533..540
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 873 AA; 96371 MW; 677401D8999877C3 CRC64;
MAKKRTSGKT KSFSEAIGLQ YIFNNTITDF FLGLALLVVA VVMMLAMISF LSTGAADQSL
LENLKPGEWT NTQQLFQNYC GSMGAILSYW LMAVNFGFPA FLIPCFVVMV GFQLMNVYRV
NLWKWFFCMM VVMIWSSVTF AKFLTPIFGS LIFNPGGKHG MFVVQTLENV IGPPGLTAIL
LFVAIAFLTY ITTETITIVR KALNPIGYIS NKVKFEITNH KEKQEEDDAI DEAYRNAAQG
TVEDEEDETD ENSQAQETSQ NQMADQNEES SLQQMAEEQK DEDEKTTSPI DLDAAAADDS
QQADADKNVA APSLIQQQRE LRAQRAERER QEMAAAAAAS AHIGMDISVA TGEEKATSNT
VSNAEVLNTP INPKEPFTRY KYPTLNLLKK YDDQEVSIDE EEQKANKNRI IEVLGNFGVQ
IKTIRATVGP TITLYEIQPA EGVRISKIKN LEDDIALSLA ALGIRIIAPI PGKGTIGIEV
PNAKANIVSM ESILNSKKFQ ETKMELPIAL GKTITNEVFM VDLAKIPHLL VAGATGQGKS
VGLNAIITSL LYKKHPNELK LVLIDPKKVE FSVYSRITNK FMAAVPDEEE PIITDVTKVV
RTLNSLCVLM DSRYDLLKKA GARNIKEYNQ KYVNHRLKLT DGHEFMPYIV VIIDEFGDLI
MTAGKEVELP IARIAQLARA VGIHMIIATQ RPTTSIITGN IKANFPGRIA FKVTSAIDSK
TILDRTGANQ LIGRGDMLYL NGNEPVRVQC AFVDTPEIER INEYICNQPG PIEPMELPEP
ASEDGGVGGN GSVDARNLDP YFEEAAHAIV LSQQGSTSMI QRRFSIGYNR AGRLMDQLEA
AGIVGAAQGS KPREVLLQDE NQLNTLLMQL RNS
//
