ID A0A374V9G8_9BACE Unreviewed; 1365 AA.
AC A0A374V9G8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DXC10_09155 {ECO:0000313|EMBL:RGM47414.1};
OS Bacteroides sp. OM08-11.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=2292284 {ECO:0000313|EMBL:RGM47414.1, ECO:0000313|Proteomes:UP000262405};
RN [1] {ECO:0000313|EMBL:RGM47414.1, ECO:0000313|Proteomes:UP000262405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM08-11 {ECO:0000313|EMBL:RGM47414.1,
RC ECO:0000313|Proteomes:UP000262405};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGM47414.1}.
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DR EMBL; QSTJ01000004; RGM47414.1; -; Genomic_DNA.
DR OrthoDB; 9809670at2; -.
DR Proteomes; UP000262405; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00146; PKD; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 4.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000313|EMBL:RGM47414.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000262405};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:RGM47414.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1365
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017036449"
FT TRANSMEM 789..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 913..929
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 843..1078
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1111..1226
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1258..1357
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1159
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1365 AA; 156263 MW; 6C7431AAFA49E529 CRC64;
MKKFVLLLFS LLTILQIFAQ NDNETFYFSN LNLKDGLSQI SVIKILQDSK GFMWFATRNG
LNRYDGSEFI VYKHVPGDSL TLSDNNIISL VEDKNRNLWV GTARGLNKLD LKTNHIKRYS
DKKHGALAKV DIRSLFVDSR NRLWVGTSRG LYLYVREMDM FQRLDLNGKI KDEYISVIHE
TKEHQILIGT ATKGLFVCDM NMKEQKHFTM DTPNLRLPDN YVGTLYEDLE GHIWGGSNAG
GLFRIDIEKE NIITYHKGNS ILTTNSIRCI AESHDRLLIG TFDGLYSMNL SDNSFWKHTD
ASLERGNLSH FSIYSLFVDS SQTIWVGTYA GGVSYSSRFN NRFDFHDPTS VFDALFGIYG
SMVCTEGGCL YMATEGRGLL DYNLNNSKYY YYPIDNSSRL QYSQNIIKGL LLDGNTLWCG
TNKGTIYQFD TRTKQYKLYY QLPKEMSIYA MTPAHDGGLW IVGSDPKTGL IHLSAKKIFL
DKFPLHDGKD SCQIASSRCI LKLRDGVLLI GTRNNGLVKY DANKQEITYY NTDAKKPFSL
LNNYVTSIIR DASDRIWIGT FGGGISLYDE YKGVLKTITR EQGLIDNDVC AIVEDRDHKL
WISTSNGISE FDQEKEQFIN YNSLNGIGVY EFTPHSGMLL PNGEVCFSGN NGFVTFNPQE
LQLNSFVPPL VFTRLVVNNE VIEVGDETGI LSSVLDDVKE IDLDYSQNNI SIGYCALNFV
FARQNQYAIF LEGYDKDWNY IGNRREAYYT NLSPGTYEFK VKASNNDGVW SQETRKIRIV
VHPPIWETWY AYLFYVVTFV SVLVLIMYYI FKKQKLEREL QFQQKEQQQL EEFHQAKIRM
FTNFSHELRT PLTLIIAPLQ ELVAMPEFSS VVKNKLGLIF SNAQRLLLLV NQLMDLRKNQ
EGKLKLRIIK SDMYLFLLEI YYAFNHLAAK KSINFTFERK VEQLMAWFDK TLIEKVVFNL
LSNAMKFTPN GGKVVFSLSQ ISSSALPAEY QSELSKLPVN TEFVCLSVAD SGKGIPDEEI
KNIFAPFYQG EDDNKENVGT GIGLSLTRSI VHLHHGIITV SKNQPTGTVF NVYIPISSFV
YEEDQLVKEE TVEDVIPVDK AMHFDIEKKW TILLAEDNDE VRRYVKECLE PYFYILDVDN
GKDALELSLE KYPDLILSDI MMPKMDGLEL CSRVKQDLQL GHIPVILMTA KSMVVHIKEG
FSVGADDYIV KPFCMDVLIC RINNILESRE KLKKLYGKKF SPEAMGIEIV SGDDRFTQSF
FELIEKNISN PELGIDLLSQ ELGLSRANLY RKLKAVTELS PTELIRNKRL EVAAKLLLES
DYTVSEVAVY TGFNSHAYFT NCFKSFYGYS PSEWVQRHHE NNENV
//
