ID   A0A374VA82_9BACE        Unreviewed;       880 AA.
AC   A0A374VA82;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=DUF5117 domain-containing protein {ECO:0000313|EMBL:RGM47509.1};
GN   ORFNames=DXC10_09725 {ECO:0000313|EMBL:RGM47509.1};
OS   Bacteroides sp. OM08-11.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=2292284 {ECO:0000313|EMBL:RGM47509.1, ECO:0000313|Proteomes:UP000262405};
RN   [1] {ECO:0000313|EMBL:RGM47509.1, ECO:0000313|Proteomes:UP000262405}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM08-11 {ECO:0000313|EMBL:RGM47509.1,
RC   ECO:0000313|Proteomes:UP000262405};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGM47509.1}.
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DR   EMBL; QSTJ01000004; RGM47509.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A374VA82; -.
DR   OrthoDB; 9776599at2; -.
DR   Proteomes; UP000262405; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   CDD; cd04276; ZnMc_MMP_like_2; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR033413; DUF5117.
DR   InterPro; IPR033428; DUF5118.
DR   InterPro; IPR032534; EcxA_zinc-bd.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR034032; Zn_MMP-like_bac.
DR   PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR   PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR   Pfam; PF16313; DUF4953; 1.
DR   Pfam; PF17148; DUF5117; 1.
DR   Pfam; PF17162; DUF5118; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000262405};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..880
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017076776"
FT   DOMAIN          55..104
FT                   /note="DUF5118"
FT                   /evidence="ECO:0000259|Pfam:PF17162"
FT   DOMAIN          116..300
FT                   /note="DUF5117"
FT                   /evidence="ECO:0000259|Pfam:PF17148"
FT   DOMAIN          433..752
FT                   /note="EcxA zinc-binding"
FT                   /evidence="ECO:0000259|Pfam:PF16313"
SQ   SEQUENCE   880 AA;  99545 MW;  C78F3936B8B992ED CRC64;
     MRLKTFLPIM AATGVLMCGP AVFLRAGQTD FASPETTGWF RKKKKNDTKD SIPSKSAYEK
     LTGDGAVVRK GMFNVYQKKN DYYFEVPANL LGRDMLVVNK LQRVPSELNE AGVNRGTNYE
     NQMVRFELDK AANKLLVRQS RPLPLAPDED AIRQSVLDNY ISPLIAGFKI EAFNSDSTKM
     VVKVNDIYDG TETSINNVFT NINLGTSAIK NLSRILSIKS FENNVVATSE LTTKVTEGTT
     TVFVTVEVSS SLLLLPEKPM MGRLDSPRVG YFTNPLLNYS DGQQRVDKKP FITRWRMEPK
     PEDSERYLRG ELVEPAKPIV FYIENSTPRR WRKYIKQGIE DWQVAFERAG FKNAIIAKEL
     TDSMNVDKDD VNYSVLTYAA STKANAMGPS ILDPRSGEIL EADIMWWHNV LSMLQEWITV
     QTGTVRSGAQ GVKLSDELMG DAMRFVACHE VGHSLGLRHN MIASWAFPTD SLRSKTFTDR
     MNSTSSSIMD YARFNYVAQP EDGITALSPH IGPYDMFAIE YGYRWYGKET PEAEKELLAD
     FLGRHTDRLY KYSEAQDVRD AVDPRAQIED LGDDAILSSL LGIENLKRIV PQIIQWTTTG
     EKGQTYEEAS RLYYAVINQW NNYLYHVLAN IGGIYLENTT VGDGQKTYTF VERERQQAAL
     KFLLDQVLTY PKWLFDTEVG EYTYLLRNTP LGVVENAPTQ VLKNAQSYIL WDLLANNRLI
     RMLENESVNG KKAFTVVELM DGLHRGIFAT TERGTVPDVM TRALQKNFVD ALITAASESE
     GVKINKKLME GHFLLDNRLP LCSCDEHARR ALNSDRMGAP RELNFYGSQI NRVSDAISVK
     RGELLRIKDL LQSRLGISDI ATKYHYKDLV LRINTALGIK
//