ID   A0A374VB96_9BACE        Unreviewed;      1010 AA.
AC   A0A374VB96;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:RGM47528.1};
GN   ORFNames=DXC10_09830 {ECO:0000313|EMBL:RGM47528.1};
OS   Bacteroides sp. OM08-11.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=2292284 {ECO:0000313|EMBL:RGM47528.1, ECO:0000313|Proteomes:UP000262405};
RN   [1] {ECO:0000313|EMBL:RGM47528.1, ECO:0000313|Proteomes:UP000262405}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM08-11 {ECO:0000313|EMBL:RGM47528.1,
RC   ECO:0000313|Proteomes:UP000262405};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGM47528.1}.
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DR   EMBL; QSTJ01000004; RGM47528.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A374VB96; -.
DR   OrthoDB; 9798415at2; -.
DR   Proteomes; UP000262405; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262405};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        433..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        522..542
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        855..874
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        881..901
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        907..928
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        949..972
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        978..1005
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1010 AA;  110999 MW;  40E407B5397B4281 CRC64;
     MNLAKYSLEN TKIIYFFLAV LLIGGIFSFG RLGKKEDAPF VIKTAVIMTR YPGAEPAEVE
     RLITEPISRE IQSMSGVYKI KSESMYGLSK ITFELQPSLS AASIPQKWDE LRRKVLNIQP
     QLPVGSSIPT VSDDFGDVFG IYYGLVGDDG FSYEEMRDWA ERIKTQVITA DGVMKVALFG
     TQTEVINIFI SVSKLAGMGI DPKQLASLLQ SQNQIINTGE ISAGEQQLRI VANGTYTTVN
     DIRNQIITTP GGQVKLGDIA IIEKGYIDPP STIMHVNGKR AIGIGVSTDP QKDVVRTGEL
     VDEKLAELLP LIPVGLELES LYPENVIAKE ANNGFIINLI ESILIVIVII MLVMGMRAGL
     LIGSSLIFSI GGTLLIMSFL GVGLNRTSLA GFIIAMGMLV DNAIVVTDNA QIAIARGVNR
     RKALIEGATG PQWGLLGATF IAICSFLPLY LAPSSVAEIV KPLFIVLAIS LGLSWVLALT
     QTTTFGNFIL KAKTGNIIKD PYDKPFYHKF ASILSVLIRK KVLTLGSMVV LFILSLVIMG
     LMPQNFFPSL DKPYFRADVL YPDGYSINDV EKEMKKVETH LMQQPEVKRV SVTFGSTPLR
     YYLASTSVGP KPNFANLLVE LTESKYTKEY EEKLDTYMKV NYPNAITRTT LFKLSPAVDA
     AIEIGFIGNN VDTLVQLTNQ ALEIMHHDNE LINIRNSWGN KIPVWKPIYS QERAQPLGVS
     RQSMAQSIQI GTNGMTLGEY RQGDQVLPIL LKNNTTGSFH INDLRTLPVF GTTPETTTLE
     QVVSNFDFQY KFSNIKNYNR QMVMMAQADP RRGVNAIAAF NRIWKQVQEE IDIPEGYKMK
     FFGEQESQAE SNAALAANLP LTFFLMFVTL LFLFKTYRKP IVILLMLPLI FIGIVSGLLL
     LGKTFDFFAI LGLLGLIGMN IKNAIVLVDQ IDAETATGKT PREAVISATI TRIVPVAMAS
     GTTILGMLPL LFDAMFGGMA ATIMGGLLVA SALTLFVLPV AYCAIHKIKG
//