ID A0A374VDC1_9BACE Unreviewed; 756 AA.
AC A0A374VDC1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|EMBL:RGM50022.1};
GN ORFNames=DXC10_01680 {ECO:0000313|EMBL:RGM50022.1};
OS Bacteroides sp. OM08-11.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=2292284 {ECO:0000313|EMBL:RGM50022.1, ECO:0000313|Proteomes:UP000262405};
RN [1] {ECO:0000313|EMBL:RGM50022.1, ECO:0000313|Proteomes:UP000262405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM08-11 {ECO:0000313|EMBL:RGM50022.1,
RC ECO:0000313|Proteomes:UP000262405};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGM50022.1}.
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DR EMBL; QSTJ01000001; RGM50022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A374VDC1; -.
DR OrthoDB; 179563at2; -.
DR Proteomes; UP000262405; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR007781; NAGLU.
DR InterPro; IPR024732; NAGLU_C.
DR InterPro; IPR024240; NAGLU_N.
DR InterPro; IPR024733; NAGLU_tim-barrel.
DR PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF05089; NAGLU; 1.
DR Pfam; PF12972; NAGLU_C; 1.
DR Pfam; PF12971; NAGLU_N; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000262405};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..756
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016646861"
FT DOMAIN 26..106
FT /note="Alpha-N-acetylglucosaminidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12971"
FT DOMAIN 121..434
FT /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT /evidence="ECO:0000259|Pfam:PF05089"
FT DOMAIN 446..726
FT /note="Alpha-N-acetylglucosaminidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12972"
SQ SEQUENCE 756 AA; 86153 MW; 52412F21A4199179 CRC64;
MIRFCLFAVA MCCYCLSAWS IGTAEKAVYD LIERVTPGYS SQYRLELIPD DAGNDVYEIE
GNGKKIILRG NNSISLASAF NWYLKYTCKA HVSWFGNQLN LPKRLPQPAR KERKIINGKY
RVYMNYCTVS YTAAWWNWER WQKELDFMAM NSINMPLFSM GLDGVWYNTL LRLGFSDEEA
RAFLTGPGHA AWQWMQNIQS YGGPLPKSVI DKHVALGKKI LARQLELGMQ PIQQGFSGYV
PRELQDKYPQ AKISMKRGWC GFKATAQLDP SDPLFHEIGL VFLQEQDKIF GSYGAYAADP
FHESAPPVDT PEYLHGVGQT IHKLFQEFDK GSLWVMQAWS LREDIVKAVP RESLLILDLN
GGRTEKFKGM WGYPVVMGNL HNFGGRINMH GDMALLASNQ YKKAKERYPN VCGSGLFMEA
IEQNPVYYDL AFEIPNHADT VALKPWLAAY AERRYGAKSD AAAQAMYYLL EGPYCRGTNG
TERSSIVAAR PALDVKKSGP NAGLGIPYDP LLVIRAQREL LKDADKLSAS KPYRFDIVDV
QRQLMTNLGQ LIHKQAAAAF RAKDKAAFAL HSGRFLELLE DMDELLRTRS EYSFDRWLTE
ARSWGDTPVE KDLMEKDATS LVTIWGADGD PSIFDYSWRE WAGLVKGYYL PRWQKFYSML
QEHLDAGTEY KEEGLKLTHG REAFRANDFY SKLGDWELAF AAKTGKARMP ATQGDELQIT
RRLFNKYLKL SQEYYADFSG ADTLKEERTY ENLGED
//
