ID   A0A374WBF9_9BACE        Unreviewed;       443 AA.
AC   A0A374WBF9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:RGN47586.1};
GN   ORFNames=DXB63_08755 {ECO:0000313|EMBL:RGN47586.1};
OS   Bacteroides sp. OM05-12.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=2292283 {ECO:0000313|EMBL:RGN47586.1, ECO:0000313|Proteomes:UP000264777};
RN   [1] {ECO:0000313|EMBL:RGN47586.1, ECO:0000313|Proteomes:UP000264777}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM05-12 {ECO:0000313|EMBL:RGN47586.1,
RC   ECO:0000313|Proteomes:UP000264777};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGN47586.1}.
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DR   EMBL; QSUN01000008; RGN47586.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A374WBF9; -.
DR   OrthoDB; 1389336at2; -.
DR   Proteomes; UP000264777; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264777};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..443
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016903682"
FT   SITE            288
FT                   /note="May be important for catalysis"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ   SEQUENCE   443 AA;  51356 MW;  0B9E8AF3C3100113 CRC64;
     MTKNTLFKSL LVFAVLCLTT THFCNADTKE KKYIPTEENM NSREAFRDDK FGIFLHWGLY
     SMLARGEWTM TNQNLNRDEY AKLASGFYPS KFDAHEWVSA IKASGAKYIC FTTRHHEGFS
     MFHTQWSDYN IVDATPFKRD VLKELADECH KQGIALHLYY SHLDWYREDY YPLGRTGRGT
     GRTKHGEWKT YYQFMNNQLT ELLTNYGPIR TIWFDGWWDH DQDPDFDWQL PEQYAMIHRL
     QPSCLIGNNH HQIPFAGEDI QIFERDLPGE NSSGLSGQDI SALPLETCET MNGMWGYKIT
     DQEYKSPKTL IHYLVKAAGK NANLLMNIGP QPNGELPEIA ISRLKEIGEW MKIYGETIYG
     TRSGSVAPHD WGVTTRKENR MFVHILDLPD NGLYLPMTEK VKKAVVFKDK TPIKYMQDKQ
     GVVLKFKEAP TDIDYVIELT LAD
//