ID A0A377PSU9_9HELI Unreviewed; 604 AA.
AC A0A377PSU9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=NADH dehydrogenase subunit M {ECO:0000313|EMBL:STQ85482.1};
DE EC=1.6.5.11 {ECO:0000313|EMBL:STQ85482.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:STQ85482.1};
DE SubName: Full=NADH-quinone oxidoreductase subunit M {ECO:0000313|EMBL:TLD99405.1};
DE EC=1.6.5.- {ECO:0000313|EMBL:TLD99405.1};
GN Name=nuoM {ECO:0000313|EMBL:STQ85482.1};
GN ORFNames=LS73_007360 {ECO:0000313|EMBL:TLD99405.1}, NCTC12714_00267
GN {ECO:0000313|EMBL:STQ85482.1};
OS Helicobacter muridarum.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=216 {ECO:0000313|EMBL:STQ85482.1, ECO:0000313|Proteomes:UP000255139};
RN [1] {ECO:0000313|EMBL:TLD99405.1, ECO:0000313|Proteomes:UP000029922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST1 {ECO:0000313|EMBL:TLD99405.1,
RC ECO:0000313|Proteomes:UP000029922};
RX PubMed=25428971;
RA Sheh A., Shen Z., Fox J.G.;
RT "Draft genome sequences of eight enterohepatic helicobacter species
RT isolated from both laboratory and wild rodents.";
RL Genome Announc. 2:e01218-e01214(2014).
RN [2] {ECO:0000313|EMBL:STQ85482.1, ECO:0000313|Proteomes:UP000255139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12714 {ECO:0000313|EMBL:STQ85482.1,
RC ECO:0000313|Proteomes:UP000255139};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
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DR EMBL; UGJE01000002; STQ85482.1; -; Genomic_DNA.
DR EMBL; JRPD02000018; TLD99405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A377PSU9; -.
DR OrthoDB; 9805769at2; -.
DR Proteomes; UP000029922; Unassembled WGS sequence.
DR Proteomes; UP000255139; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR PANTHER; PTHR43507:SF20; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:STQ85482.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000255139};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..417
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 604 AA; 67756 MW; 2BD88B8402377DEC CRC64;
MEYLLSLIIA CPLVACLFVF MFDDGGAKRF GRIISFVELG LVVALWACYL PDYVDGQFFS
TFALIPRLGV DFATSVDGIS LFLVVLTAFI MFIATIYLRR IDDAKPFVVC LLSLEGILMA
LFTSENALMF YTFWELALLP VLYIVGVWGS GQKVYIGLKF FIYTFASSLI MLLAIVYMGY
LYYQQTGMWS FNISSWKSVY INIPFETQIW LFLAFFISIA VKIPIIPFHT WLPHIYSEAP
ALGSVMLSAL LSKMGTYALL RFPLPLFPDA SIYFMPLISI LAVIMVVYAG IIAFKQSDIK
KVIAYSSISH MGIVVLGIFS FNGEGISGAV FMMVAHGITS SGLFLLAGML YYRTMTRHID
EFGGVASVMP HYSALFAIVM MSNVGLPLTI GFVGEFLSLY GFFQTSVILT AIAGTTLIIS
ASYMLYLFKN VFYGYSYLQN KTFFGNLKDL NFKEYCAIMP IIAVIIWLGV FPNTLLKPMQ
ISVQKLIATM YTLSINQISK DHLLSVNGGL IGPMIDHFYD NSIYKLKPLS KEEKEELINS
EFENHLSYCI QQYGNRLHIS NDEYKDISNC LILLNSNRGL NSNFQKNESN ALNADSQTIG
VSNE
//
