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Database: UniProt
Entry: A0A377YWM1_KLEPO
LinkDB: A0A377YWM1_KLEPO
Original site: A0A377YWM1_KLEPO 
ID   A0A377YWM1_KLEPO        Unreviewed;      1609 AA.
AC   A0A377YWM1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   07-APR-2021, entry version 7.
DE   SubName: Full=Conjugal transfer nickase/helicase TraI {ECO:0000313|EMBL:STU55207.1};
GN   Name=traI_3 {ECO:0000313|EMBL:STU55207.1};
GN   ORFNames=NCTC5050_00156 {ECO:0000313|EMBL:STU55207.1};
OS   Klebsiella pneumoniae subsp. ozaenae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=574 {ECO:0000313|EMBL:STU55207.1, ECO:0000313|Proteomes:UP000255382};
RN   [1] {ECO:0000313|EMBL:STU55207.1, ECO:0000313|Proteomes:UP000255382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC5050 {ECO:0000313|EMBL:STU55207.1,
RC   ECO:0000313|Proteomes:UP000255382};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UGLZ01000002; STU55207.1; -; Genomic_DNA.
DR   EnsemblBacteria; STU55207; STU55207; NCTC5050_00156.
DR   Proteomes; UP000255382; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0000746; P:conjugation; IEA:InterPro.
DR   InterPro; IPR014059; Conjug_relaxase_N.
DR   InterPro; IPR014129; Conjug_relaxase_TraI.
DR   InterPro; IPR009767; DNA_helicase_TraI.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR040668; TraI_2B.
DR   InterPro; IPR040987; TraI_N.
DR   InterPro; IPR014862; TrwC.
DR   Pfam; PF18272; ssDNA_TraI_N; 1.
DR   Pfam; PF07057; TraI; 1.
DR   Pfam; PF18340; TraI_2B; 1.
DR   Pfam; PF08751; TrwC; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02686; relax_trwC; 1.
DR   TIGRFAMs; TIGR02760; TraI_TIGR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:STU55207.1};
KW   Helicase {ECO:0000313|EMBL:STU55207.1};
KW   Hydrolase {ECO:0000313|EMBL:STU55207.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:STU55207.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000255382}.
FT   DOMAIN          10..283
FT                   /note="TrwC"
FT                   /evidence="ECO:0000259|Pfam:PF08751"
FT   DOMAIN          575..626
FT                   /note="ssDNA_TraI_N"
FT                   /evidence="ECO:0000259|Pfam:PF18272"
FT   DOMAIN          633..712
FT                   /note="TraI_2B"
FT                   /evidence="ECO:0000259|Pfam:PF18340"
FT   DOMAIN          1434..1556
FT                   /note="TraI"
FT                   /evidence="ECO:0000259|Pfam:PF07057"
SQ   SEQUENCE   1609 AA;  174933 MW;  32E846DF2A013A64 CRC64;
     MLSFSVVKSA GSAGNYYTDK DNYYVLGSMG ERWAGQGAEQ LGLQGSVDKD VFTRLLEGRL
     PDGADLSRMQ DGSNKHRPGY DLTFSAPKSV SMMAMLGGDK RLIDAHNQAV DFAVRQVEAL
     ASTRVMTDGQ SETVLTGNLV MALFNHDTSR DQDPQLHTHV VVANVTQHNG EWKTLSSDKV
     GKTGFSENVL ANRIAFGKIY QSELRQRVEA LGYETEVVGK HGMWEMPGVP VEAFSGRSQA
     IREAVGEDAS LKSRDVAALD TRKSKQHVDP EVRMAEWMQT LKETGFDIRA YRDAADQRAE
     TRTQAPGAVS QEGPDVQQAV TQAIAGLSER KVQFTYTDVL ARTVGILPPE NGVIERARAG
     IDEAISREQL IPLDREKGLF TSGIHVLDEL SVRALSRDIM KQNRVTVHPE KSVPRMAGYS
     DAVSVLAQDR PSLAIVSGQG GAAGQRERVA ELAMMAREQG REVQIIAADR RSQMNLKQDE
     RLSGELITGR RQLQEGMVFT PGSTVIVDQG EKLSLKETLT LLDGAARHNV QVLITDSGQR
     TGTGSALMAM KDAGVNTYRW QGGEQRPATI ISEPDRNVRY ARLAGDFAAS VKAGEESVAQ
     VSGVREQAIL TQAIRSELKT QGVLGHPEVT MTALSPVWLD SRSRYLRDMY RPGMVMEQWN
     PETRSHDRYV IDRVTAQSHS LTLRDAQGET QVVRISSLDS SWSLFRPEKM PVADGERLRV
     TGKIPGLRVS GGDRLQVTSV SEDAMTVVVP GRAEPATLPV ADSPFTALKL ENGWVETPGH
     SVSDSAKVFA SVTQMAMDNA TLNGLARSGR DVRLYSSLDE TRTAEKLARH PSFTVVSEQI
     KARAGETSLE TAISLQKAGL HTPAQQAIHL ALPVLESKNL AFSMVDLLTE AKSFAAEGTG
     FTELGGEINA QIKRGDLLYV DVAKGYGTGL LVSRASYEAE KSILRHILEG KEAVTPLMER
     VPGELMETLT SGQRAATRMI LETSDRFTVV QGYAGVGKTT QFRAVMSAVN MLPASERPRV
     VGLGPTHRAV GEMRSAGVDA QTLASFLHDT QLQQRSGETP DFSNTLFLLD ESSMVGNTDM
     ARAYALIAAG GGRAVASGDT DQLQAIAPGQ PFRLQQTRSA ADVVIMKEIV RQTPELREAV
     YSLINRDVER ALSGLESVKP SQVPRLEGAW APEHSVTEFS HSQEAKLAEA QQKAMLKGEA
     FPDVPMTLYE AIVRDYTGRT PEAREQTLIV THLNEDRRVL NSMIHDAREK AGELGKEQVM
     VPVLNTANIR DGELRRLSTW ENNPNALALV DNVYHRIAGI SRDDGLITLE DAEGNTRLIS
     PREAVAEGVT LYTPDKIRVG TGDRMRFTKS DRERGYVANS VWTVTAVSGD SVTLSDGQQT
     RVIRPGQERA VQHIDLAYAI TAHGAQGASE TFAIALEGTE GNRKQMAGFE SAYVALSRMK
     QHVQVYTDNR QGWTDAINNA VQKGTAHDVF EPKPDREVMN AQRLFSTARE LRDVAAGRAV
     LRQAGLAGGD SPARFIAPGR KYPQPYVALP AFDRNGRSAG IWLNPLTTDD GNGLRGFSGE
     GRVKGSGDAQ FVALQGSRNG ESLLAGNMGE GVRMARDNPD TGGGGAAGR
//
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