ID A0A378BT49_KLEPO Unreviewed; 361 AA.
AC A0A378BT49;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Co/Zn/Cd efflux system membrane fusion protein {ECO:0000313|EMBL:STV51305.1};
GN Name=mdtE_1 {ECO:0000313|EMBL:STV51305.1};
GN ORFNames=NCTC5050_05638 {ECO:0000313|EMBL:STV51305.1};
OS Klebsiella pneumoniae subsp. ozaenae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=574 {ECO:0000313|EMBL:STV51305.1, ECO:0000313|Proteomes:UP000255382};
RN [1] {ECO:0000313|EMBL:STV51305.1, ECO:0000313|Proteomes:UP000255382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC5050 {ECO:0000313|EMBL:STV51305.1,
RC ECO:0000313|Proteomes:UP000255382};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; UGLZ01000005; STV51305.1; -; Genomic_DNA.
DR RefSeq; WP_004147662.1; NZ_NWDO01000011.1.
DR AlphaFoldDB; A0A378BT49; -.
DR Proteomes; UP000255382; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF20; LIPOPROTEIN-RELATED; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000255382}.
FT DOMAIN 61..251
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 123..150
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 361 AA; 39254 MW; EC5B2D5FB91041BD CRC64;
MNRYFSLIPV VIIFTTACDQ KAPTVESAPR MVKVAQVTAV GNTQQRTFPA RIESGDSTEL
SFKRGGQVES LDIRQGASVA QGQTLARLNA REAQQRVNER QTAATLAQRQ FDRFQTLAGR
QAISQAEMDV QRANRDAANA ALKIAREELA QMSLIAPFSG IAAGVHIRNH QVVAAGQPVI
TLTRTDLLDV VFSIPENLFT SLDIRNTAYR PVVRINTLPG REFTAEYKEH TGSSDNSTLT
WQIVLTMPRP DDFPAVGGVS GTVTVNLGNL PASAGRETLI VPAEAVFNPD NRPKNEPVVW
VVKGDNAHRY LEERKVTVGE VTSQGVAITD GLRAGEQVVA AGVSELHAGQ PVRVWTRERG
L
//
