ID   A0A378JPA6_9GAMM        Unreviewed;       807 AA.
AC   A0A378JPA6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 10.
DE   SubName: Full=Karyopherin (Importin) beta {ECO:0000313|EMBL:STX55594.1};
GN   ORFNames=NCTC13315_02965 {ECO:0000313|EMBL:STX55594.1};
OS   Legionella beliardensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=91822 {ECO:0000313|EMBL:STX55594.1, ECO:0000313|Proteomes:UP000254968};
RN   [1] {ECO:0000313|EMBL:STX55594.1, ECO:0000313|Proteomes:UP000254968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC13315 {ECO:0000313|EMBL:STX55594.1,
RC   ECO:0000313|Proteomes:UP000254968};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family.
CC       {ECO:0000256|ARBA:ARBA00038332}.
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DR   EMBL; UGNV01000003; STX55594.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A378JPA6; -.
DR   OrthoDB; 5657127at2; -.
DR   Proteomes; UP000254968; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR032682; Cnd1_C.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR10648:SF4; PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED; 1.
DR   PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR   Pfam; PF12717; Cnd1; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   SMART; SM01349; TOG; 2.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 5.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000254968};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          233..454
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          461..682
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
SQ   SEQUENCE   807 AA;  89650 MW;  3DF3E566FA0EAD4B CRC64;
     MRSSFNFFAH LPADPPLLLI YSILPAQELY LKCRLLDKQQ SFLATLALLE KQEQVAVVYQ
     QRLLMDLLQS QTHPIITTVT FSAVAHNRLL NALWMLMKNP FWELTSKLAV IQLVGQLKGQ
     AFVLANSMLD EIETKLSSEH SKEICQGLQL LTVLLPGFIA TAKFGALLPA VQEKLADNDW
     EVREAALRCL ALLIPCLSPR EVSVLLPDVQ LKLANNDWNV REAALRCLAL LIPHLSPSEV
     SALLPDVQLK LADNIWQVRK VALNCLALLI PRLSPWEMSA LLSDVQVKLA DNIWYVREAA
     LNCLALLIPC LSPSEVSALL SDVQVKLADN DWNVREAALN CLAPFIPRLP PREVSALLPN
     VQVKLADDIW KVREAALRCL ALLIPRLSPR EVSALLSDVQ VKLANNDLDI RKAALNCLAL
     LIPHLSPSEV NALLPDVQVK LADDIWKVRK AALNCLALLI PCLSPREVSA LLSDVQVKLA
     NNIWEVREAA LNCLALLIPR LSPREVSALL SDVQVKLANS IWEVREAALN CLALLIPRLS
     PREVSALLPD VQVKLADHDW RRKQAAIRCL ALLIPCLSPR EVGALLPDVQ VKLADHGWEV
     REVALNCLAL LIPCLSPSEV SALLPDMQVK LADHDLAVRK AALRCLVLLI PRLPPKEVSA
     LLSDVQMKLA DNDLRVGQAA LNCLSVLIPR MSPSEVRQLL PVIKERLTDT NTAIYEAAGL
     CLITLVPKLT YAEQHKFIRE EGVSLVNTYP KLFYQLINGL ISQARKKDRL QLLQLASESD
     LFLQTFVTNY KMLLIEQLPS TNLQSNP
//