ID A0A378KAZ6_9GAMM Unreviewed; 434 AA.
AC A0A378KAZ6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=UDP-glucose/GDP-mannose dehydrogenase {ECO:0000313|EMBL:STX81353.1};
DE EC=1.1.1.22 {ECO:0000313|EMBL:STX81353.1};
GN Name=tuaD {ECO:0000313|EMBL:STX81353.1};
GN ORFNames=NCTC13316_03222 {ECO:0000313|EMBL:STX81353.1};
OS Legionella busanensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=190655 {ECO:0000313|EMBL:STX81353.1, ECO:0000313|Proteomes:UP000254794};
RN [1] {ECO:0000313|EMBL:STX81353.1, ECO:0000313|Proteomes:UP000254794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13316 {ECO:0000313|EMBL:STX81353.1,
RC ECO:0000313|Proteomes:UP000254794};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; UGOD01000003; STX81353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A378KAZ6; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000254794; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:STX81353.1}.
FT DOMAIN 327..425
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 434 AA; 48643 MW; 8425F0DDDED2FE40 CRC64;
MLSSFIEKIN NKEAIIAIVG LGYVGLPLML RFAEVGYRVI GIDVDESKNE SLNHGKSYIK
HIPNERISNV KKLFIATSDF SKSKEADAII LCVPTPLNKY REPDLSFVLQ TMDSLQPFLQ
RDQLISLEST TYPGTTQEEL KPRIESTGLK VGEDIFLVYS PEREDPGNPD FSTATIPKVC
GGDTENCRTA GRALYSSIIH HIVSVSNTKV AEMTKLLENI HRSVNIGLVN EIKMLADKMN
IDIHEVIEAA STKPFGFVAY NPGPGIGGHC IPIDPFYLTW KAREYGIHTR FIELAGEINS
HMPHWVVNKV AQAMNERECT IKNSRILVLG IAYKRDIDDV RESPSIEIME LLQERGAFVD
YSDPHVPSFP QMRAHKFDLL SVEITESTIN QYDCVILTTA HQAFNYELIA KNAKLIVDTR
GAFRKFNNAN IVSA
//
