ID A0A378UEE5_BERDE Unreviewed; 374 AA.
AC A0A378UEE5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN Name=potA_1 {ECO:0000313|EMBL:STZ75788.1};
GN Synonyms=potA {ECO:0000256|RuleBase:RU364083};
GN ORFNames=NCTC10295_00541 {ECO:0000313|EMBL:STZ75788.1};
OS Bergeriella denitrificans (Neisseria denitrificans).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Bergeriella.
OX NCBI_TaxID=494 {ECO:0000313|EMBL:STZ75788.1, ECO:0000313|Proteomes:UP000254651};
RN [1] {ECO:0000313|EMBL:STZ75788.1, ECO:0000313|Proteomes:UP000254651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10295 {ECO:0000313|EMBL:STZ75788.1,
RC ECO:0000313|Proteomes:UP000254651};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC spermidine/putrescine import. Responsible for energy coupling to the
CC transport system. {ECO:0000256|RuleBase:RU364083}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP
CC + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.;
CC EC=7.6.2.11; Evidence={ECO:0000256|RuleBase:RU364083};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PotA),
CC two transmembrane proteins (PotB and PotC) and a solute-binding protein
CC (PotD). {ECO:0000256|RuleBase:RU364083}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC {ECO:0000256|RuleBase:RU364083}.
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DR EMBL; UGQS01000001; STZ75788.1; -; Genomic_DNA.
DR RefSeq; WP_066080316.1; NZ_UGQS01000001.1.
DR AlphaFoldDB; A0A378UEE5; -.
DR Proteomes; UP000254651; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015417; F:ABC-type polyamine transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005893; PotA-like.
DR InterPro; IPR013611; Transp-assoc_OB_typ2.
DR NCBIfam; TIGR01187; potA; 1.
DR PANTHER; PTHR42781:SF5; PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTG; 1.
DR PANTHER; PTHR42781; SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08402; TOBE_2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF50331; MOP-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU364083};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364083}; Hydrolase {ECO:0000313|EMBL:STZ75788.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364083};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU364083};
KW Reference proteome {ECO:0000313|Proteomes:UP000254651};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU364083};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU364083}.
FT DOMAIN 13..243
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 374 AA; 42234 MW; 8023A4AA5BC4A3DD CRC64;
MTAHTASSAK PYLQIQGLVK KFGDNYAVDN IDLDIYQHEI FALLGSSGSG KSTLLRMLAG
MEIPNQGKII LDGQDITKLA PYDRPINMMF QSYALFPHMT VEQNIAFGLK QDKMPKGEID
ARVEEMLRLV QMTKFAKRKP HQLSGGQQQR IALARSLAKR PKILLLDEPL GALDKKLRQQ
TQFELVNTLE QVGVTCIMVT HDQEEAMTMA TRIAIMSEGQ LQQVGTPADV YDYPNSRFTA
EFIGETNIFE GVVIEDHADY AVIECEGLEK HVRIDHGLGG PAEQDLWVSI RPEDIDLYKE
KPDHLGDFNW AQGTVKEIAY LGSFAIYHIK LANGRVIKSQ VPAPYWYVRN ITPPTWDETV
YVSWPENQPT PLFR
//
