ID   A0A378UKN8_BERDE        Unreviewed;       109 AA.
AC   A0A378UKN8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Putative small multidrug resistance protein {ECO:0000313|EMBL:STZ77061.1};
GN   Name=emrE {ECO:0000313|EMBL:STZ77061.1};
GN   ORFNames=NCTC10295_01862 {ECO:0000313|EMBL:STZ77061.1};
OS   Bergeriella denitrificans (Neisseria denitrificans).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Bergeriella.
OX   NCBI_TaxID=494 {ECO:0000313|EMBL:STZ77061.1, ECO:0000313|Proteomes:UP000254651};
RN   [1] {ECO:0000313|EMBL:STZ77061.1, ECO:0000313|Proteomes:UP000254651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC10295 {ECO:0000313|EMBL:STZ77061.1,
RC   ECO:0000313|Proteomes:UP000254651};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC       {ECO:0000256|ARBA:ARBA00038032, ECO:0000256|RuleBase:RU003942}.
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DR   EMBL; UGQS01000002; STZ77061.1; -; Genomic_DNA.
DR   RefSeq; WP_066080118.1; NZ_UGQS01000002.1.
DR   AlphaFoldDB; A0A378UKN8; -.
DR   Proteomes; UP000254651; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561:SF1; MULTIDRUG TRANSPORTER EMRE; 1.
DR   PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000254651};
KW   Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   109 AA;  11543 MW;  D46A3B62C89039F0 CRC64;
     MNAYLMLGAA IVCEVFGTTM LKYSGGFSKW GFACAGLAAF GVAFFLVARV FETLPMGLVY
     ATWSGCGIIL TLLIGWLLGQ RPDWPAVIGV VLIIAGVLVI NLLSKTSAH
//