ID A0A378YFH9_9NOCA Unreviewed; 403 AA.
AC A0A378YFH9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=dnaX_2 {ECO:0000313|EMBL:SUA75483.1};
GN ORFNames=NCTC1934_02102 {ECO:0000313|EMBL:SUA75483.1};
OS Nocardia otitidiscaviarum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1823 {ECO:0000313|EMBL:SUA75483.1, ECO:0000313|Proteomes:UP000255467};
RN [1] {ECO:0000313|EMBL:SUA75483.1, ECO:0000313|Proteomes:UP000255467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC1934 {ECO:0000313|EMBL:SUA75483.1,
RC ECO:0000313|Proteomes:UP000255467};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UGRY01000002; SUA75483.1; -; Genomic_DNA.
DR RefSeq; WP_039809099.1; NZ_UGRY01000002.1.
DR AlphaFoldDB; A0A378YFH9; -.
DR STRING; 1406858.GCA_000710895_05992; -.
DR OrthoDB; 9809531at2; -.
DR Proteomes; UP000255467; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF70; POSSIBLE DNA POLYMERASE; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:SUA75483.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000255467};
KW Transferase {ECO:0000313|EMBL:SUA75483.1}.
FT DOMAIN 35..178
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 274..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 42351 MW; 162C7C32AD57A204 CRC64;
MAGVFDRLVG QDAVESELTA AAVAARNGTG SSSAMTHSWL FTGPPGSGRS VAALAFAAAL
QCTDPERPGC GRCHACTTTM AGTHGDVRRV VPEGLSIGTK EMRAIVQVAS RRPSTGRWQV
VVVEDADRLT EAAGNVLLKV VEEPPERTVF LLCAPSVDPE DISVTLRSRC RHVHLVTPSV
DAIARVLVER DGLDAKTAGW AASISGGHVG RARRLATDDE ARSRRKRALA LVGATARPGA
AYAAADALVK SADEEAKQVS AERDGKEREE LATAMGAGGT GKGTASATRG SAGALKDLER
RQKSRATRTG RDALDRALID VAGLYRDALA VRLRATTPDA QGVALTHPDM SDQIRDLATE
VRPEGLLRSI QAVLECREAL DTNVKPRFAV AAMVATLIAA RST
//
