ID A0A378YGG6_9NOCA Unreviewed; 848 AA.
AC A0A378YGG6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Probable ATP-dependent Clp protease ATP-binding subunit {ECO:0000313|EMBL:SUA75601.1};
GN Name=clpC_3 {ECO:0000313|EMBL:SUA75601.1};
GN ORFNames=NCTC1934_02158 {ECO:0000313|EMBL:SUA75601.1};
OS Nocardia otitidiscaviarum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1823 {ECO:0000313|EMBL:SUA75601.1, ECO:0000313|Proteomes:UP000255467};
RN [1] {ECO:0000313|EMBL:SUA75601.1, ECO:0000313|Proteomes:UP000255467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC1934 {ECO:0000313|EMBL:SUA75601.1,
RC ECO:0000313|Proteomes:UP000255467};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UGRY01000002; SUA75601.1; -; Genomic_DNA.
DR RefSeq; WP_039808955.1; NZ_UGRY01000002.1.
DR AlphaFoldDB; A0A378YGG6; -.
DR STRING; 1406858.GCA_000710895_06051; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000255467; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SUA75601.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:SUA75601.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:SUA75601.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000255467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 422..457
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 827..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 848 AA; 94005 MW; A75CA3FFBEB0EC5F CRC64;
MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKSLE SLGISLEGVR
SQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
AQVLVKLGAD LNRVRQQVIQ LLSGYQGKEP VESGTRGEAG TPSTSLVLDQ FGRNLTQAAL
EGKLDPVIGR SKEIERVMQV LSRRTKNNPV LIGEPGVGKT AVVEGLAQAI VNGEVPETLK
DKQLYTLDLG SLVAGSRYRG DFEERLKKVL KEINTRGDII LFIDELHTLV GAGAAEGAID
AASILKPKLA RGELQTIGAT TLDEYRKYIE KDAALERRFQ PVQVGEPTVE HTINILKGLR
DRYEAHHRVS ITDGALVAAA TLADRYINDR FLPDKAIDLI DEAGARMRIR RMTAPPDLRE
FDDKIADARR EKESAIDAQD FEKAARLRDK EKQLVAKRGE REKQWRSGDL DVVAEVDDEQ
IAEVLANWTG IPVFKLTEEE TTRLLRMEDE LHKRIIGQED AVKAVSKAIR RTRAGLKDPK
RPSGSFIFAG PSGVGKTELS KALANFLFGD DDALIQIDMG EFHDRFTASR LFGAPPGYVG
YEEGGQLTEK VRRKPFSVVL FDEIEKAHQE IYNTLLQVLE DGRLTDGQGR TVDFKNTVLI
FTSNLGTQDI SKAVGLGFAQ SNSEGSNYER MKLKVNDELK KHFRPEFLNR IDDVIVFHQL
TQDQIIEMVD LMISRVAVQL KNKDMAIELT DKAKSLLAKR GFDPVLGARP LRRTIQREIE
DQLSEKILFG ELGAGQTVLV DVENWDGEGQ GEDAKFTFTG KMKLTKKDSA EEKPVVALAG
ESSAASGE
//
