ID A0A378YTW9_9NOCA Unreviewed; 335 AA.
AC A0A378YTW9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=NADPH-dependent curcumin reductase {ECO:0000313|EMBL:SUA79859.1};
DE EC=1.3.1.- {ECO:0000313|EMBL:SUA79859.1};
GN Name=curA_3 {ECO:0000313|EMBL:SUA79859.1};
GN ORFNames=NCTC1934_03999 {ECO:0000313|EMBL:SUA79859.1};
OS Nocardia otitidiscaviarum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1823 {ECO:0000313|EMBL:SUA79859.1, ECO:0000313|Proteomes:UP000255467};
RN [1] {ECO:0000313|EMBL:SUA79859.1, ECO:0000313|Proteomes:UP000255467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC1934 {ECO:0000313|EMBL:SUA79859.1,
RC ECO:0000313|Proteomes:UP000255467};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UGRY01000002; SUA79859.1; -; Genomic_DNA.
DR RefSeq; WP_039815688.1; NZ_UGRY01000002.1.
DR AlphaFoldDB; A0A378YTW9; -.
DR STRING; 1406858.GCA_000710895_04436; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000255467; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:SUA79859.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000255467}.
FT DOMAIN 18..332
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 335 AA; 35432 MW; 576397A1C5CD8288 CRC64;
MSFSSREWHL VARPVGEPVP ADFSLVTTTV PDPGPGQIVV RNDFVSVDPY MRGRMNEGES
YIPQFELGEA MTGSAVGTVV ASESEDVPVG ATVSHFQGWR EYALLDAAQA QVVDPKLAPA
QAYLGVLGTT GLTAWGGLKE VAPVREGDVV FISGAAGAVG SVAGQLARQL GASRVIGSAG
GPEKVRRLTE EFGYDVGIDY RAGDLVEQLR KAAPDGIDVY FDNAGGDHLD AALVTMNRYG
RIALCGAISV YNDTELRPGP KHLPLAIGKR ITLRGMNVSD HLHLAPDFIP QAATWLAEGT
LATEETVVDG IDNAVDAFLA MMRGANTGKM LVRLS
//
