ID A0A379MMZ6_9BACT Unreviewed; 616 AA.
AC A0A379MMZ6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=L-ornithine N(alpha)-acyltransferase {ECO:0000256|ARBA:ARBA00039866};
DE EC=2.3.2.30 {ECO:0000256|ARBA:ARBA00039058};
GN ORFNames=NCTC11190_00289 {ECO:0000313|EMBL:SUE33094.1};
OS Rikenella microfusus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Rikenella.
OX NCBI_TaxID=28139 {ECO:0000313|EMBL:SUE33094.1, ECO:0000313|Proteomes:UP000255233};
RN [1] {ECO:0000313|EMBL:SUE33094.1, ECO:0000313|Proteomes:UP000255233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC11190 {ECO:0000313|EMBL:SUE33094.1,
RC ECO:0000313|Proteomes:UP000255233};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + L-ornithine = a lyso-ornithine
CC lipid + H(+) + holo-[ACP]; Xref=Rhea:RHEA:20633, Rhea:RHEA-COMP:9685,
CC Rhea:RHEA-COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:64479, ChEBI:CHEBI:78827, ChEBI:CHEBI:138482;
CC EC=2.3.2.30; Evidence={ECO:0000256|ARBA:ARBA00036203};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20634;
CC Evidence={ECO:0000256|ARBA:ARBA00036203};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. OlsB subfamily.
CC {ECO:0000256|ARBA:ARBA00038095}.
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DR EMBL; UGVL01000001; SUE33094.1; -; Genomic_DNA.
DR RefSeq; WP_037291600.1; NZ_UGVL01000001.1.
DR AlphaFoldDB; A0A379MMZ6; -.
DR STRING; 880526.GCA_000427365_01154; -.
DR GeneID; 78538955; -.
DR OrthoDB; 1113830at2; -.
DR Proteomes; UP000255233; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07986; LPLAT_ACT14924-like; 1.
DR InterPro; IPR045746; ACT14924-like_Acyltransf_dom.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR37323; GCN5-RELATED N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR37323:SF1; L-ORNITHINE N(ALPHA)-ACYLTRANSFERASE; 1.
DR Pfam; PF13444; Acetyltransf_5; 1.
DR Pfam; PF19576; Acyltransf_2; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:SUE33094.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Reference proteome {ECO:0000313|Proteomes:UP000255233};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SUE33094.1}.
FT DOMAIN 78..199
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 616 AA; 68504 MW; 243FFFB4899F0BC2 CRC64;
MKKLVDNSDL GIPYTTVLNK AVVKLAQSML GINKINRLYS EASGKEGIDF ARAVLDQLGI
VAETDAGRLG FIPEKGPFVL VSNHPHGALD GLLLMVLVAR IRPDVKFLGN FLLTKIDTLN
EFFLPVDPFD AKNGRNISGV RRAVEHLKAG RPLVVFPAGE VSTYRKGFSK IEDKPWSRSV
SKLILRAGVP VIPAYIEGCN SLIFHLLGKI HPMLRTVRLP LELINKKGRS VAVAFGSAVP
AKLLKEIGSA ESVSDFLRAN VYCLRSVLTD TAAATEELEA VRRATVSRLG FRKKRKAGGG
KSVADELAEP VDPLLLGREL DALADERMLT RVGNMCLFCA PTSVIPLTMK EIARLREVTF
RAVGEGTQLE TDSDEYDDLY EHLFVWDAEK QAIAGAYRIG FGDVLLDNRG FEGFYTYTLF
EFSRRLNDVL RQSIELGRSF VVPGYQRRSQ TLLLLWRGIL HVLLRNPSYR YLMGPVSMSG
GYAMAAKWLL IDYIKANHWN AELARYVVPR NGVGALGRPA VDEEMIRRIV STDEIDKLIR
DVEPSGQGMP VLMKKYLQLG GRVMGFNIDP LFNDALDAML ILDLCDVPKD KIDMVAREFA
GENVYERFRS VGNTKL
//
