ID   A0A380K2I0_9STRE        Unreviewed;       349 AA.
AC   A0A380K2I0;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Type I restriction-modification system, DNA-methyltransferase subunit M {ECO:0000313|EMBL:SUN58242.1};
DE            EC=2.1.1.72 {ECO:0000313|EMBL:SUN58242.1};
GN   Name=hsdM_1 {ECO:0000313|EMBL:SUN58242.1};
GN   ORFNames=NCTC12224_00271 {ECO:0000313|EMBL:SUN58242.1};
OS   Streptococcus hyointestinalis.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1337 {ECO:0000313|EMBL:SUN58242.1, ECO:0000313|Proteomes:UP000254924};
RN   [1] {ECO:0000313|EMBL:SUN58242.1, ECO:0000313|Proteomes:UP000254924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC12224 {ECO:0000313|EMBL:SUN58242.1,
RC   ECO:0000313|Proteomes:UP000254924};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UHFN01000006; SUN58242.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A380K2I0; -.
DR   REBASE; 418221; M.Shy12224ORF271P.
DR   Proteomes; UP000254924; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR   PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SUN58242.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000254924};
KW   Transferase {ECO:0000313|EMBL:SUN58242.1}.
FT   DOMAIN          2..309
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
SQ   SEQUENCE   349 AA;  39388 MW;  58EE02597781DC18 CRC64;
     MLGRTYEYCL EQFAAYEGKN GGEFYTPTSI VKTIVEILKP FNGRVYDPAC GSGGMFVQSE
     TFIENHSGNI NNLSIYGQEA NADTWKMAKI NMAIRGIEPN FGPHQADTFT NDLHPTLKAD
     YIMANPPFNL KKWGADKLAD DVRWKYGTPP DSNANYAWIQ HMIHHLAPNG KIGLVLANGS
     LSSTQSGEGD IRKAIIEDDL VEGIVALPAQ LFYSVTIPAC LWFISKNKKQ KGKTVFIDAR
     NLGHMVDRKH RDFTDDDIQK IAKTFEAFQE GTLENEKGFC AVVETEDIAE QDYILTPGRY
     VGVEDREEDS EPFEEKMERL TAELSELFKQ SHVLEEEIKQ RLEEIGFEI
//