ID A0A380KF46_9STRE Unreviewed; 271 AA.
AC A0A380KF46;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative hemolysin {ECO:0000313|EMBL:SUN62880.1};
DE EC=2.1.1.226 {ECO:0000313|EMBL:SUN62880.1};
GN Name=tlyA {ECO:0000313|EMBL:SUN62880.1};
GN ORFNames=NCTC12224_02119 {ECO:0000313|EMBL:SUN62880.1};
OS Streptococcus hyointestinalis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1337 {ECO:0000313|EMBL:SUN62880.1, ECO:0000313|Proteomes:UP000254924};
RN [1] {ECO:0000313|EMBL:SUN62880.1, ECO:0000313|Proteomes:UP000254924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12224 {ECO:0000313|EMBL:SUN62880.1,
RC ECO:0000313|Proteomes:UP000254924};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
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DR EMBL; UHFN01000007; SUN62880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A380KF46; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000254924; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SUN62880.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000254924};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transferase {ECO:0000313|EMBL:SUN62880.1}.
FT DOMAIN 62..245
FT /note="Ribosomal RNA methyltransferase FtsJ"
FT /evidence="ECO:0000259|Pfam:PF01728"
SQ SEQUENCE 271 AA; 29844 MW; 1D11681B9A021348 CRC64;
MAKERVDVLA YKQGLFETRE QAKRGVMAGL VIAVLNGERF DKPGEKIDSS TELKLKGEKL
RYVSRGGLKL EKALDVFGIS VEGATTLDIG ASTGGFTDVM LQSGAKLVYA VDVGTNQLVW
KLRQDERVIS MEQYNFRYAE PSDFTQGQPT FASIDVSFIS LGLILPALAK VLADGGEVVA
LIKPQFEAGR EYIGKNGIVK DKKVHEMVIQ QVCQFALESG YTVCGLDFSP IQGGHGNIEF
LAHLKKEDNP QNLVMNQIDT IIEKAHEEFK K
//
