ID   A0A380M7T4_9ACTO        Unreviewed;       285 AA.
AC   A0A380M7T4;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Sortase (Surface protein transpeptidase) {ECO:0000313|EMBL:SUO86460.1};
GN   ORFNames=NCTC5224_00115 {ECO:0000313|EMBL:SUO86460.1};
OS   Trueperella pyogenes.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Trueperella.
OX   NCBI_TaxID=1661 {ECO:0000313|EMBL:SUO86460.1, ECO:0000313|Proteomes:UP000254485};
RN   [1] {ECO:0000313|EMBL:SUO86460.1, ECO:0000313|Proteomes:UP000254485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC5224 {ECO:0000313|EMBL:SUO86460.1,
RC   ECO:0000313|Proteomes:UP000254485};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UHHW01000002; SUO86460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A380M7T4; -.
DR   Proteomes; UP000254485; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05827; Sortase_C; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR042002; Sortase_C.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   NCBIfam; NF033745; class_C_sortase; 1.
DR   NCBIfam; TIGR01076; sortase_fam; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..285
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016723882"
FT   TRANSMEM        254..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        148
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        210
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   285 AA;  30622 MW;  5E0E043ABBD69E84 CRC64;
     MKVRSLAVVL TMLLAAAIVS VAPLVEHVRN DSATINVANT YLREHSTANP HDTEALSAAA
     TYNAELSHRL LDDPWADSAA HTGDAYNHYL SLLADTPVMA TLTIPAINAR LPIVHGTSDE
     ALLNGVGHFY GSHLPVGGKG THAVLAGHHT WPGHTYFSNL EDLKIGDHFT IDAYGATLAY
     DVVDINLVRP DDLAKIQPQP GRDLVTLVTC ITPEGGKLNE FRLLVTAERA LETPADAAPA
     PAADIPTVQI QTWMYPRIIT ASVALALALI FTGLWLRNRK GTNRA
//