ID A0A380NMU9_9FIRM Unreviewed; 653 AA.
AC A0A380NMU9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=EIIABC-Fru {ECO:0000313|EMBL:SUP44243.1};
GN Name=fruA {ECO:0000313|EMBL:SUP44243.1};
GN ORFNames=NCTC12020_01573 {ECO:0000313|EMBL:SUP44243.1};
OS Veillonella criceti.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Veillonella.
OX NCBI_TaxID=103891 {ECO:0000313|EMBL:SUP44243.1, ECO:0000313|Proteomes:UP000255367};
RN [1] {ECO:0000313|EMBL:SUP44243.1, ECO:0000313|Proteomes:UP000255367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12020 {ECO:0000313|EMBL:SUP44243.1,
RC ECO:0000313|Proteomes:UP000255367};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UHIO01000001; SUP44243.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A380NMU9; -.
DR OrthoDB; 9782569at2; -.
DR Proteomes; UP000255367; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR GO; GO:0022877; F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR CDD; cd05569; PTS_IIB_fructose; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013014; PTS_EIIC_2.
DR InterPro; IPR004715; PTS_IIA_fruc.
DR InterPro; IPR003353; PTS_IIB_fruc.
DR InterPro; IPR006327; PTS_IIC_fruc.
DR NCBIfam; TIGR00829; FRU; 1.
DR NCBIfam; TIGR00848; fruA; 1.
DR NCBIfam; TIGR01427; PTS_IIC_fructo; 1.
DR PANTHER; PTHR30505; FRUCTOSE-LIKE PERMEASE; 1.
DR PANTHER; PTHR30505:SF28; PTS SYSTEM 2-O-ALPHA-MANNOSYL-D-GLYCERATE-SPECIFIC EIIABC COMPONENT; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000255367};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 588..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..149
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
FT DOMAIN 196..291
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 319..653
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 653 AA; 67811 MW; 8E925A4A8957349E CRC64;
MKITDLLKKQ SIQLNASPST KDEAICHLAD LMEASGNLRN KEQYIKDVLI REESGSTGLG
MGLATPHAKS IGVKAPGLAA MTVPAGMDFE SLDGEPSRLF FMIAAPEGEA DTHVQVLANL
ATLIMDPAFK EALIKAQTVE GFLALIDVKE ADQFKPKMTE TEALAIVEQN VTPATTAAPQ
TTDTATNVTL ANHYQVLAVT ACPTGIAHTA MAAEALSRTA ADMGISIKVE QNGASGVKDA
LTADDIAQAD CIIVAADKSV PMARFNGKPL IQVKVADGIN KAKELLTEAT SGQAAIYKAN
GEDNTSSTVT ANDSIGRQIY KHLMNGVSHM LPFVIGGGIL IALAFLFDDF NPADPSKFGS
GTELAAFFMK IGGASFSFML PVLAGFIGMS IADRPGLAVG FVGGYLANAG GSGFLGALLA
GFVAGYLMLL LKKAFSGLPH TLEGIKPVLL YPVLGVLLMG IIITFIINPP VGALNESLMN
ALKSMNTSSR VVIGLIFAGM MAVDMGGPVN KAAYVIGTGL LATGEYGVMA AVMAGGMVPP
LAIALCTTFF PNRFTPAERK SGITNYIMGL SFITEGAIPF AAADPIRVIP SCIIGAAVAG
ALSMAFECTL RAPHGGIFVV PTIGNPLMYL GAILIGSVVT ALLLAILKKP LKD
//
