ID A0A380PE94_YERPE Unreviewed; 891 AA.
AC A0A380PE94; A0A2S9PFQ5; A0A3G5LA52; A0A6B3T6D2; Q0WCW6;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Clp ATPase {ECO:0000313|EMBL:CAL21552.1};
DE SubName: Full=Type VI secretion system ATPase TssH {ECO:0000313|EMBL:AYX22131.1};
GN Name=clpB5 {ECO:0000313|EMBL:CAL21552.1};
GN Synonyms=tssH {ECO:0000313|EMBL:AYX22131.1};
GN OrderedLocusNames=YPO2946 {ECO:0000313|EMBL:CAL21552.1};
GN ORFNames=EGX46_14320 {ECO:0000313|EMBL:AYX22131.1};
OS Yersinia pestis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632 {ECO:0000313|EMBL:CAL21552.1, ECO:0000313|Proteomes:UP000000815};
RN [1] {ECO:0000313|EMBL:CAL21552.1, ECO:0000313|Proteomes:UP000000815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis {ECO:0000313|Proteomes:UP000000815},
RC and CO92 {ECO:0000313|EMBL:CAL21552.1};
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Leather S., Karlyshev A.V., Moule S.,
RA Oyston P.C.F., Quail M., Rutherford K., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2] {ECO:0000313|EMBL:CAL21552.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CO92 {ECO:0000313|EMBL:CAL21552.1};
RX PubMed=12834539; DOI=10.1186/1471-2180-3-13;
RA Delihas N.;
RT "Annotation and evolutionary relationships of a small regulatory RNA gene
RT micF and its target ompF in Yersinia species.";
RL BMC Microbiol. 3:13-13(2003).
RN [3] {ECO:0000313|Proteomes:UP000275238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_601;
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Jaissle J.,
RA Tallon L., Sadzewicz L., Zhao X., Vavikolanu K., Mehta A., Aluvathingal J.,
RA Nadendla S., Yan Y., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AYX22131.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FDAARGOS_601 {ECO:0000313|EMBL:AYX22131.1};
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Jaissle J.,
RA Tallon L.J., Sadzewicz L., Zhao X., Vavikolanu K., Mehta A.,
RA Aluvathingal J., Nadendla S., Yan Y., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP033699; AYX22131.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL21552.1; -; Genomic_DNA.
DR PIR; AE0358; AE0358.
DR RefSeq; WP_002215317.1; NZ_WUCL01000029.1.
DR RefSeq; YP_002347872.1; NC_003143.1.
DR AlphaFoldDB; A0A380PE94; -.
DR GeneID; 57975756; -.
DR KEGG; ype:YPO2946; -.
DR KEGG; ypj:CH55_4132; -.
DR KEGG; ypl:CH46_2159; -.
DR KEGG; ypv:BZ15_585; -.
DR KEGG; ypw:CH59_3128; -.
DR PATRIC; fig|214092.21.peg.3396; -.
DR OMA; HRDVHEM; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000275238; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR017729; ATPase_T6SS_ClpV1.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03345; VI_ClpV1; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF184; ATPASE WITH CHAPERONE ACTIVITY-RELATED; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000000815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 9..150
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
SQ SEQUENCE 891 AA; 97758 MW; 773AAC37B88931E3 CRC64;
MAITRKHLFG KLDATLFKGI ESATTICKLR GNPYVELVHW LNQLWHQEDN DLKQIIRYFA
VDVDAFEREL AQALAKLPVG ATSISDFSYH IELATERAWI YASLECLDTR IRSGHLLLAL
LTTMELRRAF FAIAPSMEKI PLEHLSKDLN FITQASPEAN EAASDGSPLY DGALPGEASN
AIGAAKSGGA LAQYTTDLTA LAREGKIDPV LGRNHEINTM VDILLRRRQN NPLLTGDAGV
GKTAIVEGLA LAIAAGSMPP ALSQVSLLSL DIVALSAGAS MKGEFEARLK SVLDEAIAAE
KPVILFIDEV HTLIGAGGNA GTGDAANLLK PALARGQLRT IGATTWSEFK RHIEKDPALT
RRFQVLQVDE PDENTAISML RGLIPALEKH HGVWIMDEAL QAAVRLSHRY IPARQLPDKA
ISLLDTACAR IAVAQFSQPI ELQHLTFQSE TAQTELVSLE KARHFGKAQD ARTEQLKTSI
AEHGEAADKL DQRWQAEREL VSAITTIRTA LYDLVSQPEP DEEKRRAYQA QLVQLEAQLS
QVRTSLPLVQ TEVNAEVIAS IVADWTGIPV GQMLKDDIRA VMELPQRLEA RVIGQPHALM
QLGENIMTAR AGLSDPRKPL GVFMLVGPSG VGKTETALAI AESMYGGEQN MITINMSEYQ
ESHTVSSLKG SPPGYVGYGE GGVLTEAVRR KPYSVVLLDE IEKAHSDVHE LFFQVFDKGQ
MEDGEGRFID FKNTILLLTS NVGSELLSNL LADPDTAPDQ DGILSALQPE LLKVFPAAFL
GRVTVIPYLP LQQDALQHIV RLHLDRIGAR LYSQHQLTLK YSDEVVEDVV SRCAVSETGA
RMLIRYIEQN ITPKIGKYIL GDSDVKPEQI IFVHKNENGF VIALQCKDDE N
//
