ID A0A381E6K5_9GAMM Unreviewed; 240 AA.
AC A0A381E6K5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Lipopolysaccharide export system ATP-binding protein LptB {ECO:0000256|ARBA:ARBA00017803};
GN Name=lptB {ECO:0000313|EMBL:SUX22155.1};
GN ORFNames=NCTC13294_01182 {ECO:0000313|EMBL:SUX22155.1};
OS Cardiobacterium valvarum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC Cardiobacteriaceae; Cardiobacterium.
OX NCBI_TaxID=194702 {ECO:0000313|EMBL:SUX22155.1, ECO:0000313|Proteomes:UP000254572};
RN [1] {ECO:0000313|EMBL:SUX22155.1, ECO:0000313|Proteomes:UP000254572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13294 {ECO:0000313|EMBL:SUX22155.1,
RC ECO:0000313|Proteomes:UP000254572};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex LptBFG involved in the
CC translocation of lipopolysaccharide (LPS) from the inner membrane to
CC the outer membrane. Probably responsible for energy coupling to the
CC transport system. {ECO:0000256|ARBA:ARBA00024818}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. The LptBFG transporter is composed of two ATP-binding proteins
CC (LptB) and two transmembrane proteins (LptF and LptG).
CC {ECO:0000256|ARBA:ARBA00026081}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004515}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004515}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004515}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Outer membrane
CC lipopolysaccharide export (TC 1.B.42) family.
CC {ECO:0000256|ARBA:ARBA00010865}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UFUW01000001; SUX22155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A381E6K5; -.
DR OrthoDB; 9781337at2; -.
DR Proteomes; UP000254572; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd03218; ABC_YhbG; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR032823; BCA_ABC_TP_C.
DR InterPro; IPR030921; LPS_export_LptB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR04406; LPS_export_lptB; 1.
DR PANTHER; PTHR45772; CONSERVED COMPONENT OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS-RELATED; 1.
DR PANTHER; PTHR45772:SF10; LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF12399; BCA_ABC_TP_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SUX22155.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000313|EMBL:SUX22155.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000254572}.
FT DOMAIN 2..235
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 240 AA; 26420 MW; E38F094139637B57 CRC64;
MLIAEKLQKT YRKRRVVNDA SFQVDAAKVV GLLGPNGAGK TTSFYMTIGL VRPDHGHILL
DGTDITRLPV HRRAQLGLSY LPQEASVFRK LSVRDNILAI LELATSLGKH EREARAQELM
QDLGIADRAD IPGQSLSGGE RRRCEIARTL ACNPRFILLD EPFAGVDPIA VGDIRNIITH
LTDRGIGVLI TDHNVRETLK SCDYAYILSE GSVIAAGSPA EIVANEEARR VYLGEDFELH
//
