ID   A0A383S2V2_9ACTN        Unreviewed;       748 AA.
AC   A0A383S2V2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Sterol-sensing domain {ECO:0000313|EMBL:SYZ32267.1};
GN   ORFNames=PROPAUS_0142 {ECO:0000313|EMBL:SYZ32267.1};
OS   Propionibacterium australiense.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Propionibacterium.
OX   NCBI_TaxID=119981 {ECO:0000313|EMBL:SYZ32267.1, ECO:0000313|Proteomes:UP000263928};
RN   [1] {ECO:0000313|Proteomes:UP000263928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hornung B.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UNQJ01000001; SYZ32267.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A383S2V2; -.
DR   Proteomes; UP000263928; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000263928};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   748 AA;  79049 MW;  E60A09325AAD0843 CRC64;
     MFDQIGRTVS RHPALFIIAW MLLLSAMVYL TFQGMGHGGL FDRLTSTNAP TPDTESDRVT
     SLTTSDETDG ETVTVIISDV DMGNDPAELS AAVSMARKTL SDLEDVVSVQ DAFMMPDPSS
     QEAKALLSSS GDGYVELVTL AEGLDDERSQ AANDRVAKTA EGAYLDALRQ HSPNANAHAV
     SSKLISDSIG QLVQKDLAQG ESVSLPVALV LLVIVFGGLL AAGLPLVNAV ISILVGMGAL
     WCLTFALDVH SFILNVISIL GLALSIDYGL LFVSRYREEA AAQLARAGWN DGELPAGDAM
     KDLVRATVVR TVATAGRTVS FSALTIACSI AGLLVLRTPM FKTIAAGAAI VALVAVLGTV
     TLVPAIITLL GARLVRPSAL SRVPGLRRVL AAVGDTSSDD GVFSRLSRRV VAHPWIVILT
     IAAALSVMAS PVVSMHMRTN IIEYMPAGSS VRAGYDILQD DYPALASPTI SIVAQTDPTT
     AAGFVSDLGA MDDVTHVTAT DLADHEHMTL ISVLMDVDDP VGPRATDAVD QIRAIDPGYQ
     VWVGGQAAQQ TDFIDAMVDR APWAALIVVA AVFVLLFCMT GSLIIPLKAL IINTFSLVAS
     LGATAWLFQG GHLGLPQTAG MQTFIVACLM AFGFGLAMDY EVFLLARITE YWQAGYDNDE
     AVARGLQRSG RIITSAAAII IAVFLGFVSG EMISIKELGV GLAIMVAADA TLVRLLLVPA
     TMTVLGQWNW WAPGPLAKLY RHFLPGKS
//