ID A0A383VS64_TETOB Unreviewed; 4214 AA.
AC A0A383VS64;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SZX68365.1};
GN ORFNames=BQ4739_LOCUS8724 {ECO:0000313|EMBL:SZX68365.1};
OS Tetradesmus obliquus (Green alga) (Acutodesmus obliquus).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Scenedesmaceae; Tetradesmus.
OX NCBI_TaxID=3088 {ECO:0000313|EMBL:SZX68365.1, ECO:0000313|Proteomes:UP000256970};
RN [1] {ECO:0000313|EMBL:SZX68365.1, ECO:0000313|Proteomes:UP000256970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Cai Z.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNXT01000852; SZX68365.1; -; Genomic_DNA.
DR STRING; 3088.A0A383VS64; -.
DR Proteomes; UP000256970; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000256970};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 877..1288
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1428..1754
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1922..2061
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2281..2370
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2443..2701
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2715..3056
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 3087..3308
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3555..3667
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3702..3843
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3910..4210
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 124..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3866..3892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 801..861
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2943..3005
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 193..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4214 AA; 465294 MW; 9314256ADC9216C6 CRC64;
MEDTRDPLEG PAYNPFQHPL VWCLQDFLAQ RNSNCSGDGA SDAAGGNLED SFVCNQQHAA
ALKVVEQRRK LPPVLNDKAL FTRAAPFGDR ADQAYHAPSN RIGVYYSPGS MAAAAQLFEE
FPQDPHAPRT RAGAKPLGDI RSPYSSSRPL SPSHAGELSP TAAAVAAMGR PLSPSHSPKV
QAAALLASKA AGLHQQPPQQ QQHGTRLSSS TGAAPPAAAA AVDEASLVDA LLRYCYYQEV
GIDARHVAPF REEWMGNALL MVPNQPPPNV SDAFFDHFIS SAMQEVRTDY SKAMQRAMLD
YVLSNALERQ RLGLQGLEPL LVPRHGLRGP LGPPLGSDSQ QRLVQRQLPQ EWHEHVALAR
EDIAWTLQTL SPNALELSRL WHDSGYISAR LLDVASRELR DRLPVKADWF KQYQQSATEQ
VKGQLWSHWL PKCVDVFRRL PPVPINGDTE AYFRAVATLQ SNQLRGLVAA SLSDYMAFFK
QHKAVQQLDP QQDSCMWSCR PVFETELVAV QGQVTFEPSF QDTQAAALSA LEGAVVAAMG
LPKITPSSIS SSSLAAPPAS TNAASMASNP TVIPSTGLTE ELVQQTAQEI LSILQANSAA
PLQLAALFGP YLYLLQLDPV EHAQSFAAGA GGAESPDLTQ FKEEIERLQA AALAVRLLCT
DTVRAGLYHV QCRKFKDQLI GAADAAVHNL LDIVCTAAAH SNLRVFDEYQ VMTAEVGKAS
NNGEEVLALK KFISKCNLDN EKLKDVIAVN KGRDDFLLKF RFPVPDEDID SARKAYEWPK
RFADVLREAG TKAAAEHRQF EAALKARRKE FDKRVEQYAA ELALVEGRND IVKREVVASE
VADLQAKLQA AVAEAEEINN QEKMFGWALT KYAHVSKLLA TVEPYVGLWT TINDFYNSYS
VWMNGPFWKL SPEQVEAEAA DAYRKLFKLT KVFSAGAAGE ARELPLAVAE EGRSKVSGFQ
AYTPLIAAVC NPGLRERHWA AMAEIVGFEI KQDEVTSLRR LLDNDILEHL MRIGELSDSA
SREFSIEKAL DKMAADWEGL AFELGTWKAT GTHILKGGPV EEAQMLLDDH VVKSQAMAAS
PFSKPFEERL VPWERKLRRF QEMLDEWLTC QGKWLYLEPI FGAEEIMKQI PKEGSAFRAM
DASWRRIMAQ VHEQPLMMAV ADTPDLLEQL KECNQQLDVV EKGLNDFLET KKMAFPRFYF
LSNDELLEIL SEAKDPLAVQ PFVKKCFEAV KELVFEANEE ISGMVSQEGE KITFTERVNP
ATSGAVECWL LEVQAAMKRT MHSITREALA AYPKAPRTSW ILQWPGQLVL NGSQVFWTRE
VTDAIQSGGA KGLSLYAHKC SQELAKLVSL VRGSLSNLER ATCGALVVID VHARDVTSHM
AAEGVEDVRD FKWESQLRYY WEHNEAPPSG VKPQETIMVR MINAEALYGY EYLGNSGRLV
ITPLTDRCYR TLMGAIHMNL GGAPAGPAGT GKTETTKDLS KALAIQCVVF NCSDGLDYKA
MGKFFKGLAC SGAWACFDEF NRIELEVLSV VAQQVLTIIR AKAAKVATFL FEGAEIPINM
TCNCFITMNP GYAGRSELPD NLKALFRDVA MMVPDYAMIA EIMLYSYGYL YARALARKLV
QTYRLCSEQL SSQDHYDYGM RAVMSVLRAA GNLKRSFASA PEDVLMLRAI NDVNLPKFLD
QDVPLFNGIL SDLFPGVELP SVDYDNLRNA LIDNCVKAGL QPLESFLTKA IQLYEMIVVR
HGLMLVGQSY GMKTAAYRML AGALTDLNAK GLNNEFATKM YVLNPKSISM GQLYGQEDPI
SKEWTDGVLP TLFRSAARDT SPDRKWLVFD GPVDALWIEN MNTVLDDNKK LCLNSGEIIA
MQGLMNMIFE VADLAVASPA TVSRCGMVYV QPDLLGWRPV MLSWLAALPA GITEAQKAQM
LALADWLVPP CLRAATKLMK AVLPMVDINL VCSLMRLLES HLDEFSNGNA ALAELPEQQQ
AALLQCHFLF SLVWSIGANT DDEGRKTFDG LLRKLLAGDA PPQLADFITA PEVPIFVQFP
EGRLVYDFVL DRSKLKWVPW LDRLESKALD TDAEYSSIIV PTMDTLRYTY LLDALVQHKH
HCLFVGPTGT GKTVYVKRHL QTGLPAASFT SMLMTFSAQT SANMTQDIID GKLEKRRRGV
YGPPAGKSMV VFVDDLNMPQ VEVYGAQPPI ELLRHGIDHN AWYDRKELAL RKLEGLQYVA
AMGPPGGGRN NVTHRYLRHF SIVSMTAFDR DNLQLIFSAL VDWWLRKFSY SQNIGKLAKG
LVGATLDVYE SVQKQLLPTP TKSHYTFNLR DVSKVFQGMT KAAGSVEDSH SGVRLWAHEV
LRVFYDRLID EPDRLRVGRL LEELTEKHFK QQLGRLLGLA GAGGAAVADD ELLGGLRGLI
FGDFMVPGAD VKVYKDITDQ DKMLHVVGEY LADMNAGSKK PQNLVLFQFA LEHVARISRI
ITSPGGNALL VGLGGSGRQS LTRLAAYMQD MEVFQIEISK TYGQTEWHDD LRKVLKPAGE
ANKKVVFLFS DTQIKDESFV EDLSNLLNTY EVPNLIGSGD LAGIFENIRP RAKHAGMDGS
RDQLYNFFVQ EVRRNLHIVL SFSPVGDAFR ERLRKFPSLV NCTTLDWFTA WPRDALATVA
TNFLAGLPGA DDKVARALPV LCVKFHEDVQ ALSARFLAEQ QRHYYVTPTS YLELLGSYKK
LLAKRQDEVM TAKTRYEVGL SKLATTESSV TGMQEELIAL QPQLEDSTRQ TEAAMVVIAR
ETAEADKVKK VVSQEEASAS AEAAKVQAIK DECEADLAEA MPALQAAVRA LDTLTKNDIT
EVKGMKSPPA AVRVVLEAVC ILKGIKPVRF KDPQSGQMVD SYWEASKKML MDEEFLLSLR
QFDKDHIDAG IMKKITGYTV LPEFQPDKIE KVSKAAYGLC CWVRAMEVYD RVAKVVGPKK
EALKQAEGEL EVVMTALRAK QAELQAVLDK LAALDADLAE KTARKESLEA EVELCKVKLD
RAQKLIAGLG GEKSRWTAAA ARLGQEYQQL TGDVLLAAAS IAYLGAFTST YRSDCLHGWV
EACKAHGVAC SEKFKLGVVL SDPVKVRQWN IWGLPKDDFS TENAIAIDAG RRWPLCIDPQ
GLANKWIRAM EKDAGLLVIK LTDANFLRTL ENAIQFGKPV LLENVGEVLD ASLEPLLARQ
TFKQAGSLCI KLGDAVVEYS DGFKFYITTK LRNPHYAPEL CTKVSLLNFM TTPEGLEDQL
LGIVVAAERP DLEEEKAKLI ISGAANKRKL KETEDEILRV LSSGSGNILE DEAAVNILQS
SKILADEISS KQKIADETEQ KIDQAREEYK PVAHHASLLY FSVSDLAAID PMYQYSLRWF
VELFTRAIAD SMRSPDLPTR LQLLNVHFTY FLYQNVCRSL FEKDKLLFAF TLALKLRLDA
GAVGQQELRF LMTGGVAVGD LPLPNPAPDW IADKCWGELC RASDLGPAWQ GLAAHVAEHL
DEWRVLYDSA APQSEPLPGD WQGRLDAFQR LLLLRAMRQD KLTPAIMAYV AEVMGGRFVE
PQPFALEPSF ADSSAATPLI FVLSPGSDPM AALLKFADDR GVRVESVSLG QGQGPVATKL
IEKGSTAGFW VVLQNCHLAK SFMTTLELLC ESLLAEGRCH SSFRLWLTSY PSPEFPISVL
ENSIKMTNEP PKGLRAGLLR TYVSDPFCSS DFLEGCVHDA PFRRLLLGLA FFHSVLQERR
KFGPIGFNIP YEFNENDLRI SCRQLRMFLD EYPDIPYDTL AYTAGECNYG GKVTDGHDRH
TLMTLLSTYY SPALVSTAGY SLAGTPTDRY AVPEHTNYKG YLDYINSLPL STAPAVFGLH
DNADIAKDLQ ESQLLLDSLL LTQSSSSTPA PAAPKPAAGP RSSTAASSTG AAAAADAQDS
SASGTAAAAA AAVPAIRSPE DVIAEVAADI LGRLPPNFDL EAAERAYPQD YYNSMNTVLV
QELGRFNSLL SVMRSTLLAL DQACKGLALM SAELDALGRS LFDGKVPGLW LRKSFPSLKP
LGGYLREVLE RVAFFSGWLQ HGAPPVYWIS GFFFTQAFLT GAKQNYARKL KLPIDTIDFD
FEIMDGLPEA AATGAAAAAG ADGEAVAAPA DGVYCRGLFL EGARWDSSSH ELVESHPKVL
FTQMPVIWMV PKDVSSFSQY PHYNCPLYKT AERRGVLSTT GHSTNFVLDI RLPSSKDAAH
WTKRGVALLT SLSS
//
