ID A0A383VTQ6_TETOB Unreviewed; 921 AA.
AC A0A383VTQ6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SAM-dependent MTase RsmB/NOP-type domain-containing protein {ECO:0000259|PROSITE:PS51686};
GN ORFNames=BQ4739_LOCUS9193 {ECO:0000313|EMBL:SZX68877.1};
OS Tetradesmus obliquus (Green alga) (Acutodesmus obliquus).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Scenedesmaceae; Tetradesmus.
OX NCBI_TaxID=3088 {ECO:0000313|EMBL:SZX68877.1, ECO:0000313|Proteomes:UP000256970};
RN [1] {ECO:0000313|EMBL:SZX68877.1, ECO:0000313|Proteomes:UP000256970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Cai Z.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
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DR EMBL; FNXT01000885; SZX68877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A383VTQ6; -.
DR STRING; 3088.A0A383VTQ6; -.
DR Proteomes; UP000256970; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0016428; F:tRNA (cytidine-5-)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030488; P:tRNA methylation; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR023270; RCMT_NCL1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22808; NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22808:SF1; RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR PRINTS; PR02011; RCMTNCL1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000256970};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 68..464
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 896..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..911
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 360
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 188..194
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 226
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 307
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 921 AA; 99507 MW; F160C69AA91D10D1 CRC64;
MGRGGRGGHK KRLMRKDYQG DGKRENAWNE KKTHRADQYL EAGDMHNEAF EEYYKVQDIV
PEGEWQEFLD ILKKPLPITF RINGSGRFAA ELVTKLQTDF FSHFSEGPVM LDGELVQPPR
PLPWYPSNLA WHMNFTRNQL RKLSWLAAIH EFMKVANEAG SITRQEAVSM VPPLFMDVQP
HHRVLDMCAA PGSKTFQLLE MLHNMEGADS SSGSSTTPSG FVVANDADAQ RCNLLTHQTK
RMCSPCLMVT NHNGEQFPKI TGLQPAPGSA AAAAAAVEAA AAELAGNAAQ QQQGEGEVMR
FDRILCDVPC SGDGTMRKAP DIWRRWSVNN GNGLHNMQLR IALHAVRLLK VGGRMVYSTC
TPNPIEDEAV VAELLVRCKG ALQLLDVSDQ LPELKRCAGK RKWLVRDKHQ WYSNWEEAAK
VGFKLDPTMF SSPEKQQLPL ERCMRILPHH QDTGGFFVAV LQKVAETPDL PDPSLAHRFT
RIITAGRDGR LIKIDGADPH QGAEDAAAYA LEAAEQAIAA LEAGDAAAAT KAANAAAAAA
SRGGLAQDAA TEIYKNQRRY DSQEARKQQQ LAKQQQRQQD AATAGADEDA AAVEADADAD
VQAMEGVETA GDDVDADADA AAAAADEAEG ADDAADGAAD GKAAWTPSWV RGGGGRGRSG
SGRFRGIDPI IPVEDPTIIK MLVDFYGVEA SFPLATHLIT RSLEAAFPKR LYYVSDALLA
VLLADERESL KITATGLKLF ERHELRGKEL GKCQYRIAQE GLPFLLPHLT KQVIRLPVAD
FMRLLADRNV PLLIPSSAAG SEAETAAAAA AAKTPSNQVP LSTPSVLKQL EGLESGGAVA
LLDEEAAQQL GLAVDQAGSG ALTANAPLAV SVWRTRASLS VLVAKNECEQ MADKVRSAQQ
RMKQQQQGGK GAAKQAEAVA A
//
