ID   A0A383VYF6_TETOB        Unreviewed;       496 AA.
AC   A0A383VYF6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=von Hippel-Lindau disease tumour suppressor beta domain-containing protein {ECO:0000259|Pfam:PF01847};
GN   ORFNames=BQ4739_LOCUS10707 {ECO:0000313|EMBL:SZX70495.1};
OS   Tetradesmus obliquus (Green alga) (Acutodesmus obliquus).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Sphaeropleales; Scenedesmaceae; Tetradesmus.
OX   NCBI_TaxID=3088 {ECO:0000313|EMBL:SZX70495.1, ECO:0000313|Proteomes:UP000256970};
RN   [1] {ECO:0000313|EMBL:SZX70495.1, ECO:0000313|Proteomes:UP000256970}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Cai Z.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VHL family. {ECO:0000256|ARBA:ARBA00010057}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNXT01000991; SZX70495.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A383VYF6; -.
DR   STRING; 3088.A0A383VYF6; -.
DR   Proteomes; UP000256970; Unassembled WGS sequence.
DR   CDD; cd05468; pVHL; 1.
DR   Gene3D; 2.60.40.780; von Hippel-Lindau disease tumour suppressor, beta domain; 1.
DR   InterPro; IPR024053; VHL_beta_dom.
DR   InterPro; IPR037140; VHL_beta_dom_sf.
DR   InterPro; IPR036208; VHL_sf.
DR   InterPro; IPR022772; VHL_tumour_suppress_b/a_dom.
DR   Pfam; PF01847; VHL; 1.
DR   SUPFAM; SSF49468; VHL; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000256970}.
FT   DOMAIN          71..134
FT                   /note="von Hippel-Lindau disease tumour suppressor beta"
FT                   /evidence="ECO:0000259|Pfam:PF01847"
FT   REGION          41..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  53396 MW;  7901FF38F649CAE4 CRC64;
     MATATAPVAP APASTLLTVA GLPPPDLALP VLASVNNREQ YRKRDENETE EAQWYSPDEP
     DTMVEPQQVR LKSLHSKAAS VIVFTNNSTF PVRALWLDFE GHEVVYSVLE PKSTKRYHTY
     VTHPWIVREV QSGTRMMLSG RPAVVGLSTE QTVEIQAPKQ LPWSLENHCC FSEQYKSEVK
     ALLLCQKKLE TAASCTFSKP SPARTSAVPP LPPAVPASPY RASTPFSSCS MDVCCGTPMS
     PSQSLRCTTP LSPRASFSSA NSSGSFAPRS SSPLGMLSAP DVAAPSTATS ISISSDATQF
     TATLTVTSPK RAVLSSRVNM NIEVTTGGFA NTTNINFNTV LDGSDTGIAS ASTISGCVSP
     VARKSDKKGI FNMFKNILHP KQHCKVQDQA PATTTFKLQV QTQDTQMLDQ GAACMAAPVE
     DTCWPPMGTH LGHLPSHLMV YIAELAQPVC WQTLQAQPKG RPDILPTLMA CSPNLPEEQP
     EQEQQDGDDQ APPALI
//