ID A0A383WGI6_TETOB Unreviewed; 607 AA.
AC A0A383WGI6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 03-MAY-2023, entry version 14.
DE RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(+)] {ECO:0000256|RuleBase:RU361243};
DE EC=1.1.1.8 {ECO:0000256|RuleBase:RU361243};
GN ORFNames=BQ4739_LOCUS16599 {ECO:0000313|EMBL:SZX76239.1},
GN BQ4739_LOCUS19695 {ECO:0000313|EMBL:SZX79420.1};
OS Tetradesmus obliquus (Green alga) (Acutodesmus obliquus).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Scenedesmaceae; Tetradesmus.
OX NCBI_TaxID=3088 {ECO:0000313|EMBL:SZX76239.1, ECO:0000313|Proteomes:UP000256970};
RN [1] {ECO:0000313|EMBL:SZX76239.1, ECO:0000313|Proteomes:UP000256970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Cai Z.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate
CC + H(+) + NADH; Xref=Rhea:RHEA:11092, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642,
CC ChEBI:CHEBI:57945; EC=1.1.1.8;
CC Evidence={ECO:0000256|RuleBase:RU361243};
CC -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00011009,
CC ECO:0000256|RuleBase:RU000437}.
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DR EMBL; FNXT01001251; SZX76239.1; -; Genomic_DNA.
DR EMBL; FNXT01001367; SZX79420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A383WGI6; -.
DR STRING; 3088.A0A383WGI6; -.
DR Proteomes; UP000256970; Unassembled WGS sequence.
DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0047952; F:glycerol-3-phosphate dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR HAMAP; MF_00394; NAD_Glyc3P_dehydrog; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006168; G3P_DH_NAD-dep.
DR InterPro; IPR006109; G3P_DH_NAD-dep_C.
DR InterPro; IPR011128; G3P_DH_NAD-dep_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11728; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11728:SF1; GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] 2, CHLOROPLASTIC; 1.
DR Pfam; PF07479; NAD_Gly3P_dh_C; 1.
DR Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR PRINTS; PR00077; GPDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00957; NAD_G3PDH; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|RuleBase:RU000437};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000437};
KW Reference proteome {ECO:0000313|Proteomes:UP000256970}.
FT DOMAIN 277..435
FT /note="Glycerol-3-phosphate dehydrogenase NAD-dependent N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01210"
FT DOMAIN 455..595
FT /note="Glycerol-3-phosphate dehydrogenase NAD-dependent C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07479"
FT REGION 67..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 62335 MW; 9652C4F32DEE33AF CRC64;
MPWPLSTAAA ANISPLHFQQ HHQQQQQVCW HQQQQHHRQR LRCSSVSRQS SAAGHCSSCC
AAQPAASQGF PPLVRPGSRA GQRPSRSVSL RVVALERDED YEQPPEAAGV LPDVARRLEA
DRSSSPTGSR KAAASNPISL TNPIIRAGGS SSSSSSTAGS SSPTPGSSSA PSSSSSSNGA
GPAGLSAAAP SATAPAAAAA AAAGAAMQQQ QAAASAAAAE LAGASSGPAV SPAGLSPLYP
PAERSQIQES WDALMRWSKT FSKRSGSGLS PIEAADKVVV FGGGSFGTAM GSSLALKKPQ
LDVVLLLRDP YLCKDINSSH CNTKYLPGFT LPRNVRATTD AAEAIAGAQY AVHAVPVQHS
RAFLTGVREV LPKDVPIICV SKGLEVGSGC MMSEVIPSAL GRRQPAVFLS GPSFAKEVMQ
GRPTGVVAAS KDAALAREIQ ELFASPCMRV NTSTDVTGVE ICGALKNVLA IAAGIVEGLD
LGHNALAALI AQGCAEIRWL SQKVGAKPAT ISGLSGLGDI MLTCYGDLSR NRAVGVRLGR
GEKLHDILAS STQVAEGVAT AGVVVGLARK YRVSLPVLTA VAQVLDSNLE PAEAVAAVMN
LPQIEER
//
