ID A0A383YMV9_BALAS Unreviewed; 1473 AA.
AC A0A383YMV9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Roundabout homolog 2 isoform X3 {ECO:0000313|RefSeq:XP_007164169.1};
GN Name=ROBO2 {ECO:0000313|RefSeq:XP_007164169.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007164169.1};
RN [1] {ECO:0000313|RefSeq:XP_007164169.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007164169.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
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DR RefSeq; XP_007164169.1; XM_007164107.1.
DR GeneID; 103017551; -.
DR CTD; 6092; -.
DR OrthoDB; 5396194at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR CDD; cd05726; IgI_4_Robo; 1.
DR CDD; cd20952; IgI_5_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF52; ROUNDABOUT HOMOLOG 2; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1473
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016641037"
FT TRANSMEM 864..886
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 133..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 225..309
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 318..413
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 421..508
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 528..622
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 641..739
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 743..840
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1035..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1214..1473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1217..1231
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1242..1288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1387..1403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1419..1436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1458..1473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1473 AA; 161368 MW; 62D39C03F064F2F0 CRC64;
MSRLMFTQLL LCGFLYVRVD GSRLRQEDFP PRIVEHPSDV IVSKGEPTTL NCKAEGRPTP
TIEWYKDGER VETDKDDPRS HRMLLPSGSL FFLRIVHGRR SKPDEGSYVC VARNYLGEAV
SRNASLEVAL LRDDFRQNPT DVVVAAGEPA ILECQPPRGH PEPTIYWKKD KIRIDDKEER
ISIRGGKLMI SNTRKSDAGM YTCVGTNMVG ERDSDPAELT VFERPAFLRR PINQVVLEEE
AAEFRCQVQG DPQPTVRWKK DDADLPRGRY DIKDDYTLRI KKAMSTDEGT YMCIAENRVG
KVEASATLTV RARPVAPPQF VVRPRDQIVA QGRTVTFPCE TKGNPQPAVF WQKEGSQNLL
FPNQPQQANS RCSVSPAGDL TITDTQRSDA GYYICQALTV AGSILAKAQL EVTDVLTDRP
PPIILQGPAN QTLAVDGTAL LKCKATGDPL PVISWLKEGF TFLGRDPRAT IQEQGTLQIK
NLRISDTGTY TCVATSSSGE TSWSAVLDVT ESGATISKNY DFNDLPGPPS KPQVTDVTKN
SVTLSWQPGT PGTLPASAYI IEAFSQSVSN SWQTVANHVK TTLYTVRGLR PNTIYLFMVR
AINPQGLSDP SAMSDPVRTQ DISPPAQGVD HRQVQKELGD VLVHLHTPVV LTPTTVQVTW
TVDRQPQFIQ GYRVMYRQTS GLQATSTWQN LDAKVPTERS AVLVNLKKGV TYEIKVRPYF
NEFQGMDSES KTVRTTEEAP SAPPQSVTVL TVGSHNSTSI SVSWDPPPPD HQNGIIQEYK
IWCLGNETRF HINKTVDAAI RSVIIGGLFP GIQYRVEVAA STSAGVGVKS EPQPIIIGGR
NEVVITENNN SITEQITDVV KQPAFIAGIG GACWVILMGF SIWLYWRRKK RKGLSNYAVT
FQRGDGGLMS NGSRPGLLNA GDPSYPWLAD SWPATSLPVN NSSSGPNEIA NFGRGDVLPP
VPGQGDKTAT MLSDGAIYSS IDFTTKTTYN SSSQITQATP YATTQILHSS SIHELAVDLP
DPQWKSPIQQ KTDLMGFGYS LPDQNKGNNG GKGGKKKKNK NSSKAQKNNG STWASVPLPP
PPVQPLPGTE LEHYAVELQE NGYDSDSWCP PLPVQTYLHQ GMEDELEEDD DRVPTPPVRG
VASSPAISFG QQSTATLTPS PREEMQPMLQ AHLDELTRAY QFDIAKQTWH VQSNNQPPQP
PVPPLGYMSG ALISDLETDV PDDDADDEEE ALEIPRPLRA LEQTPGSSTD NLDSSVTGKA
FTSSQRPRPT SPFSTDSNTS AAMSQSQRPR PTKKHKGGRV DPQPALPHRR EGMTDDLPPP
PDPPPGQGLR QQIGPSQHAG NVENSTERKG SSLDRQQASN LEDTKSSLDC PAKTSLEWQR
QTQEWINSTE RQEDIRKALH KQGVGPEETL VPYSKPSFPS PGGHSSSGTA SSKGSTGPRK
AEALRGSHQR NASDLLDIGY MGSNSQGQFT GEL
//
