ID   A0A383YRN0_BALAS        Unreviewed;       850 AA.
AC   A0A383YRN0;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Dipeptidyl aminopeptidase-like protein 6 {ECO:0000256|ARBA:ARBA00040948};
DE   AltName: Full=Dipeptidyl peptidase 6 {ECO:0000256|ARBA:ARBA00042016};
DE   AltName: Full=Dipeptidyl peptidase VI {ECO:0000256|ARBA:ARBA00041991};
GN   Name=DPP6 {ECO:0000313|RefSeq:XP_007165515.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007165515.1};
RN   [1] {ECO:0000313|RefSeq:XP_007165515.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007165515.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC       Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
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DR   RefSeq; XP_007165515.1; XM_007165453.2.
DR   AlphaFoldDB; A0A383YRN0; -.
DR   STRING; 310752.A0A383YRN0; -.
DR   KEGG; bacu:103009928; -.
DR   CTD; 1804; -.
DR   InParanoid; A0A383YRN0; -.
DR   OrthoDB; 2876738at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002469; Peptidase_S9B_N.
DR   PANTHER; PTHR11731:SF20; DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6; 1.
DR   PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR   Pfam; PF00930; DPPIV_N; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|RefSeq:XP_007165515.1};
KW   Hydrolase {ECO:0000313|RefSeq:XP_007165515.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Protease {ECO:0000313|RefSeq:XP_007165515.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        81..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          180..546
FT                   /note="Dipeptidylpeptidase IV N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00930"
FT   DOMAIN          627..833
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   850 AA;  95672 MW;  B19BCF7771640A99 CRC64;
     MFGGKRGGQR PEEPFQNLSS GPEREGHAQG SISVRAQRSR SPRRSRFHGS LGSTEVSCAA
     QPCLAMELVG SNPPQRNWKG IAIALLVILV ICSLIVTSVV LLTPAEDNSL SQKKKVTVED
     LFSEDFKIHD PEAKWISDKE FIYREQKGSV ILQNVETNTS TVLIEGKKIE SLRAVRYEIS
     PDREYALFSY NVEPIYQHSY TGYYVLSKIP HGDPQSLDPP EVSNAKLQYA GWGPKGQQLI
     FIFENNIYYC AHVGKQAIRV VSTGKEGVIY NGLSDWLYEE EILKTHIAHW WSPDGTRLAY
     ATINDSRVPV MELPTYTGSV YPTVKSYHYP KAGCENPSIS LHVIGLNGPT HDLEMMPPDD
     PRMREYYITM VKWATSTKVA VNWLSRAQNV SILTLCDATT GVCTKKHEDE SEAWLHRQNE
     EPVFSKDGRK FFFVRAIPQG GQGKFYHIMV SSSQPNSSND NIQSITSGDW DATKILSYDE
     KRSKIYFLST EDLPRRRQLY SANTVGNFNR QCLSCDLVDN CTYFSASFSP SADFFLLKCE
     GPGVPTVTVH NTTDKKKIFD LETNEHVQKA INDRQMPKVE YRKIEIDDYN LPVQILKPAT
     FTDTAHYPLL LVVDGAPGSQ SVAEKFEVSW ETVMVSSHGA VVVKCDGRGS GFQGTKLLHE
     VKRRLGSLEE KDQMEAVRLM LKEQYIDKTR VAVFGKDYGG YLSAYILPAK GENQGPVFTC
     GSALSPITDF KLYASAFSER YLGLHGLDNR AYEMAKVAHR VSTLEGQQLL IIHATADEKI
     HFQHTAELIT QLIKGKANYS LQIYPDESHY FSSAPLQQHL YRALISFFVE CFRIQDKLPA
     VAAKEDEEED
//