ID   A0A383Z0A0_BALAS        Unreviewed;      1134 AA.
AC   A0A383Z0A0;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Transient receptor potential cation channel subfamily M member 4 isoform X4 {ECO:0000313|RefSeq:XP_007168339.1};
GN   Name=TRPM4 {ECO:0000313|RefSeq:XP_007168339.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007168339.1};
RN   [1] {ECO:0000313|RefSeq:XP_007168339.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007168339.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   RefSeq; XP_007168339.1; XM_007168277.1.
DR   AlphaFoldDB; A0A383Z0A0; -.
DR   GeneID; 102998468; -.
DR   CTD; 54795; -.
DR   OrthoDB; 201873at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800:SF6; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 4; 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
DR   SUPFAM; SSF140860; Pseudo ankyrin repeat-like; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_007168339.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023303}.
FT   TRANSMEM        684..704
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        767..794
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        883..903
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        923..940
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1007..1040
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          89..319
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          782..1044
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          480..499
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          715..744
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1108..1134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1134 AA;  126212 MW;  478DB07702DF4E65 CRC64;
     MVGAEKEQSW IPKIFKKKTC TTFIVDPTDA GGTLCQCGQP RCAHPSVAVE DAFGAAVVTV
     WDSDLHTTEK PTDAFGDLDF LGAGRKASNF LRLSDRTDPA TVYNLVTNIW GFQAPNLVVS
     VLGGSGDPTL QTWLQDLLRR GLVRAAQNTG AWIVTGGLHK GIGRHVGVAV RDHQTARTGG
     NKVVAMGVAP WGVVRNRHTL INPKGSFPAR YRWHGDPEDG VHFPLDYNYS AFLLVDDGTH
     SRLGGENRFR LGFESYLARQ KTGVGGTGID IPVLLLLIDG DEKMLKQIEN ATQAQLPCLL
     VAGSGGAADC LAEIHTLAPG SGGGRRCEAQ DLIKRFFPEG DPEILQAQVE RIMTRKELLT
     VYSANDGPEE FETIVLKALV KACGSSEASA YLDELRLAVA WNRVDIAQSE LFRGDIRWRS
     FHLEASLMDA LLNDRPEFVR LLISHGLSLD RFLTPTRLAQ LYNAVPPNSL IHSLLDQASH
     GTGNKSPVSK PSSEPQPPKV GQVLRMLLGK TCAPTFPAGG TQQGDGSKED SYLMWDKATS
     ELVLEAIPGQ APWIDLLLWA LLLNRAQMAV YFWEMGSNSV ASALGACLLL RVLGRLETEA
     EEAARRKDLA AKFEGLGVDL FGECYRSSEE RAAHLLLWRC PLWGDATCLH LAMQADARSF
     FAQDGVQSLL TQKWWGEMDS TTPIWALVLT FFCPPLIYTN LITFRKPDEE PTQKDLAFDM
     DRDVSGEGPG ETTDPPEKTP LGVLRPPSRR SCCGGCPQRL RRWPQFWGAP VTSFMGNVVS
     YLLFLLLFAH VLLIDFQPET PSALELLLYF WAFTLLCEEF RQGLGGGLGS LAMGAPRTDS
     HQAPLRRRLH LYLSDAWNQC DLVALTCFLL GVGCRLTAGL YDLGRTVLCL DFMIFTVRLL
     HIFTVNKQLG PKIVMVNKMM KDVFFFLFFL GVWLIAYGVA TEGLLRPQDR NLANILRRVF
     YRPYLQIFGQ IPQEDIDAGL MKPDNCSSEK GLWARPSRTQ AGSCVSLYAN WLVLVLLVIF
     LLVANILLVN LLIAMFSYTF GKVQGNSDLY WKAQRYSLIR EFHSRPALAP PLIVISHVLS
     LIRRLRRRRA SLTPKAVVEH FRERPAWPKR EKPRGRNLER KKSMYRLEED AQEH
//