ID A0A383Z1Z3_BALAS Unreviewed; 709 AA.
AC A0A383Z1Z3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DNA-binding protein RFX2 {ECO:0000256|ARBA:ARBA00039910};
DE AltName: Full=Regulatory factor X 2 {ECO:0000256|ARBA:ARBA00042136};
GN Name=RFX2 {ECO:0000313|RefSeq:XP_007169173.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007169173.1};
RN [1] {ECO:0000313|RefSeq:XP_007169173.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007169173.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_007169173.1; XM_007169111.1.
DR AlphaFoldDB; A0A383Z1Z3; -.
DR GeneID; 103001335; -.
DR CTD; 5990; -.
DR OrthoDB; 2915941at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR007668; RFX1_trans_act.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF17; DNA-BINDING PROTEIN RFX2; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF04589; RFX1_trans_act; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125,
KW ECO:0000313|RefSeq:XP_007169173.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 200..275
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 709 AA; 77169 MW; E26A70BEBB9AA5BE CRC64;
MQNSEGGSDS PASVALCPSS AAQAPVAQPV PASPQRVLVQ AAGSAPKGAQ MQPISLPRVQ
QVQPVQHVYP PQVQYVEGGD AVYTNGSLRT AYAYNPEPQM YAPSSSASYF EAPGGAQVTV
AGSSPTAVPA HSMVGITMDV AGSPIVSGAG AYLIHGGMEG TRHSLAHTSR SSPATLEMAI
ENLQKSEGIT SHKSGLLNSH LQWLLDNYET AEGVSLPRSS LYNHYLRHCQ EHKLDPVNAA
SFGKLIRSVF MGLRTRRLGT RGNSKYHYYG IRLKPDSPLN RLQEDTQYMA MRQQPVHQKP
RYRPAQKTDS LGESGSHGSL HSTPEQAMAA QSQHHQQYID VSHVFPEFPA PDLGSVLLQE
NITLHDIKAL QLAYRRHCEA TLDVVMNLQF HYVEKLWLSF WNSKASSSDG PASLPARDEE
PEGAVLPKDK LVSLCKCDPV LRWMRTCDHI LYQALVEILI PDVLRPVPST LTQAIRNFAK
SLEGWLTNAM SDFPQQVIQT KEQASWVCQC EEGVVQRLEQ DFKLTLQQQS SLDQWASWLD
NVVTQVLKQH AGSPSFPKAA RQFLLKWSFY SSMVIRDLTL RSAASFGSFH LIRLLYDEYM
FYLVEHRVAE ATGETPIAVM GEFNDLASLS LTLLDKGGCV WAFPPVLGLV AIRAAPGAGT
LGSSPLGAQS KGPAPPAGLR LVLLPGSLHT RPLSAGPRTG LVPGQGLAG
//
