ID A0A383Z2P3_BALAS Unreviewed; 1543 AA.
AC A0A383Z2P3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=CLIP-associating protein 1 {ECO:0000313|RefSeq:XP_007169341.1};
GN Name=CLASP1 {ECO:0000313|RefSeq:XP_007169341.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007169341.1};
RN [1] {ECO:0000313|RefSeq:XP_007169341.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007169341.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Golgi
CC apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601}.
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DR RefSeq; XP_007169341.1; XM_007169279.1.
DR STRING; 310752.A0A383Z2P3; -.
DR KEGG; bacu:103008013; -.
DR CTD; 23332; -.
DR InParanoid; A0A383Z2P3; -.
DR OrthoDB; 5478662at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:UniProt.
DR GO; GO:0051494; P:negative regulation of cytoskeleton organization; IEA:UniProt.
DR GO; GO:1902904; P:negative regulation of supramolecular fiber organization; IEA:UniProt.
DR GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF28; CLIP-ASSOCIATING PROTEIN 1; 1.
DR Pfam; PF21040; CEP104-like_TOG; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 1.
DR SMART; SM01349; TOG; 4.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 4: Predicted;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..232
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 168..206
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 319..551
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 830..1068
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 1232..1532
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 235..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1063..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1145..1212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1251..1278
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 250..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..740
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1543 AA; 168759 MW; 5030D96B0B283867 CRC64;
MEPRMEACLA QVLQKDVGKR LQVGQELIDY FSDKQKSADL EHDQTTLDKL VDGLATFWVN
SSNYKVVLLG MDILSSLVTR LQDRFKAQIG TVLPSLIDRL GDAKDSVREQ DQALLLKIMD
QAANPQYVWD RMLGGFKHKN FRTREGTCLC LVATLNASGA HTLTLSKIVP HICNLLGDPN
SQVRDAAINS LVEIYRHVGE RVRADLSKKG LPQSRLNVIF TKFDEVQKSG NMIQSANDKN
FDDEDSVDGN RPSSASSTSS KAPASSRRNV GMGTTRRLGS STLGSKSSAA KEGAGAVDEE
DFIKAFDDVP AVQIYSSRDL EESINKIREI LSDDKHDWEQ RVNALKKIRS LLLAGAAEYD
NFFQHLRLLD GAFKLSAKDL RSQVVREACI TLGHLSSVLG NKFDHGAEAI MPTIFNLIPN
SAKIMATSGV VAVRLIIRHT HIPRLIPIIT SNCTSKSVAV RRRCFEFLDL LLQEWQTHSL
ERHISVLAET IKKGIHDADS EARIEARKCY WGFHSHFSRE AEHLYHNLEP SYQRALQSHL
KSSDSVVSLP QSDRSSSSSQ ESLNRPLSAK RSPTGSATSR ASTVSSKSVS TTGSLQRSRS
DIDVNAAASA KSKVPSAPGA APFSSAAALP PGSYASLDGT ATKAEGRIRT RRQSSGSATN
VTSTPSDSRG RSRAKVVSQS QRSRSANPAG AGSRSSSPGK LLGSGYSGLA GGSSRGPPAT
PSSEKRSKIP RSQGCSRETS PNRIGLDRFG LGQAGRIPGS VNAMRVLSTS ADLEAAVADA
LLLGDSRSKK KPVRRRYEPY GMYSDDDANS DASSVCSERS YSSRNGGVPH YLRQTEDVAE
VLNHCASSNW SERKEGLLGL QNLLKSQRTL SRVELKRLCE IFTRMFADPH SKRVFSMFLE
TLVDFIIIHK DDLQDWLFVL LTQLLKKMGA DLLGSVQAKV QKALDVTRDS FPFDQQFNIL
MRFIVDQTQT PNLKVKVAIL KYIESLARQM DPTDFINSSE TRLAVSRIIT WTTEPKSSDV
RKAAQIVLIS LFELNTPEFT MLLGALPKTF QDGATKLLHN HLKNSSHTSA GSPSNTIGRT
PSRHPSSRTS PLTSPTNCSH GGLSPSMLEY DTENLNSEEI YSSLRGVTEA IEKFSFRSQE
DLNEPIKRDG RKDCEVVSRD GGITSPATEG RGGSDAVEGG RTALDNKTSL LNTQPPRAFP
GPRARDYSPY PYSDTISTYD KTALKEAVFD DDMEQLRDVP IDHSDLVADL LKELSNHNER
VEERKGALLE LLKIAREDSL GVWEEHFKTV LLLLLETLGD KDEAFLGSLS GAGSRDVPAG
TAPALVEPAV REPPSRKPGV RVADTALLEY GCPLQPAHPA DAVGAKAWPG PGAAQRGATR
ACPWASELRR QCRLVWLELT HVRAVFQVVR AAEEAASTLA SSIHPEQCIK VLCPIIQTAD
YPINLAAIKM QTKVVERIAK ESLLQLLADI IPGLLQGYDN TESSVRKASV FCLVAIYSVI
GEELKPHLAQ LTGSKMKLLN LYIKRAQTTN SNSSSSSDVS THS
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