ID   A0A383Z3S5_BALAS        Unreviewed;       413 AA.
AC   A0A383Z3S5;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   08-NOV-2023, entry version 20.
DE   SubName: Full=Failed axon connections homolog isoform X2 {ECO:0000313|RefSeq:XP_007169722.1};
GN   Name=FAXC {ECO:0000313|RefSeq:XP_007169722.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007169722.1};
RN   [1] {ECO:0000313|RefSeq:XP_007169722.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007169722.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_007169722.1; XM_007169660.1.
DR   AlphaFoldDB; A0A383Z3S5; -.
DR   CTD; 84553; -.
DR   OrthoDB; 3684737at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd03193; GST_C_Metaxin; 1.
DR   CDD; cd03080; GST_N_Metaxin_like; 1.
DR   InterPro; IPR026928; FAX/IsoI-like.
DR   InterPro; IPR045796; FAXC_N.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR033468; Metaxin_GST.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR   PANTHER; PTHR12289; METAXIN RELATED; 1.
DR   Pfam; PF19333; FAXC_N; 1.
DR   Pfam; PF17171; GST_C_6; 1.
DR   Pfam; PF17172; GST_N_4; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SFLD; SFLDG01200; SUF1.1; 1.
DR   SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..36
FT                   /note="Failed axon connections homolog N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19333"
FT   DOMAIN          121..215
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF17172"
FT   DOMAIN          268..330
FT                   /note="Metaxin glutathione S-transferase"
FT                   /evidence="ECO:0000259|Pfam:PF17171"
FT   REGION          372..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..413
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   413 AA;  47369 MW;  1EBBB429F42A4925 CRC64;
     MAGLGSDPWW KKTLYLTGGA LLAAAAYLLH ELLVISLGKT QNNLKYVGWK IHLEMATLSE
     FTGNHILHHG TWISCCVDLI YGYISRVESK VDRKQQEIDS KDAIILHQFA RPNNGVPSLS
     PFCLKMETYL RMADLPYQNY FGGKLSAQGK MPWIEYNHEK VSGTEFIIDF LEEKLGVNLN
     KNLGPHERAI SRAVTKMVEE HFYWTLAYCQ WVDNLNETRK MLSLSGGGPF SNLLRWVVCH
     ITKGIVKREM HGHGIGRFSE EEIYMLMEKD MRSLAGLLGD KKYIMGPKLS TLDATVFGHL
     AQAMWTLPGT RPERLIKGEL INLAMYCERI RRKFWPEWHH DDDNTVYESE ESCEDSKTHT
     PLLDFSSYSR TETFEDEGAE NSFSRTPDTD FTGHSLFDSD VDLDDYTDHE QCK
//