ID A0A383Z4U1_BALAS Unreviewed; 1115 AA.
AC A0A383Z4U1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Scavenger receptor cysteine-rich type 1 protein M130 isoform X1 {ECO:0000313|RefSeq:XP_007170173.1};
GN Name=CD163 {ECO:0000313|RefSeq:XP_007170173.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007170173.1};
RN [1] {ECO:0000313|RefSeq:XP_007170173.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007170173.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR RefSeq; XP_007170173.1; XM_007170111.2.
DR AlphaFoldDB; A0A383Z4U1; -.
DR STRING; 310752.A0A383Z4U1; -.
DR KEGG; bacu:103000693; -.
DR CTD; 9332; -.
DR InParanoid; A0A383Z4U1; -.
DR OrthoDB; 5403281at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 9.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR19331:SF463; SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160; 1.
DR PANTHER; PTHR19331; SCAVENGER RECEPTOR DOMAIN-CONTAINING; 1.
DR Pfam; PF00530; SRCR; 9.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 9.
DR SUPFAM; SSF56487; SRCR-like; 9.
DR PROSITE; PS00420; SRCR_1; 4.
DR PROSITE; PS50287; SRCR_2; 9.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_007170173.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1045..1066
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..151
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 158..258
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 265..365
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 372..472
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 477..577
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 582..682
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 718..818
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 823..925
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 928..1028
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 76..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 89..150
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 120..130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 183..247
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 196..257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 227..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 290..354
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 303..364
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 334..344
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 397..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 410..471
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 441..451
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 502..566
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 515..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 546..556
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 607..671
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 620..681
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 651..661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 743..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 756..817
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 787..797
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 863..924
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 894..904
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 953..1017
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 966..1027
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 997..1007
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1115 AA; 120277 MW; C64A539DAC3875C6 CRC64;
MDKLRMVLHE NSGSTEFRRY SAHLSPFTIA VVSVLSACLV TRSLGGTDKE LRLTAGENKC
SGRVEVKVQE EWGTVCNNGW DLSAVSVVCR QLGCPTVIKA TGWANSSAGS GRIWMDHVSC
RGNESALWDC KHDGWGKHNC THQQDVGITC SDGSDLEMRL MNGGNRCSGR IEVKFQGQWG
TVCDDNFNID HASVVCKQLE CGSAVSFSGS ANFGEGSGPI WFDDLVCNGN ESALWNCKHE
GWGKHNCDHA EDAGVICLEG ADLSLRLVDG VTECSGRLEV KFQGEWGTVC DDGWDSNDAA
VACKQLGCPT AVTAIGRVNA SEGIGHIWLD SVSCHGHESA LWQCKHQEWG KHYCNHNEDA
GVTCSDGSDL GLRLKGGGSH CAGTVEVEIQ KLIGKVCDRG WGLKEADVVC RQLGCGSALK
TSYQAYSKIK ATNTWLFLSS CNGNETSLWD CKNWQWGGLS CDHYDEAKVT CSAHREPKLV
GGDIPCSGRV EVKHGDTWGT VCDSDFSLEA ASVLCRELQC GTVVSILGGA HFGEGNGQIW
AEEFQCEGHE SHLSLCPVAP RPDGTCSHSR DVGVVCSRYT EVRLVNGQSP CEGRVELKIL
GTWGSLCNSH WDMEDAHVFC QQLKCGVALS APRGAPFGKG SGQVWRHMFH CTGTERHMGD
CPMTALGASL CPLGQVASVI CSGNQSQTLP PCNSSSSDPT SSIFSEESGV PCIGSGQLRL
VNGGGRCAGR IEIYHEGSWG TICDDSWDLN DAHVVCRQLG CGGAINAVGS AHFGEGTGPI
WLDEVNCNGK ESRIWQCHSH GWGRHNCRHK EDAGVICSEF MSLRLISETS RETCAGHLEV
FYNGAWGSVG KSNMSAATVG VVCRQLGCAD RGSIIPASSD KTMSRHMWVD NVQCPKGPDT
LWQCPSSPWK KRLASPSEET WITCANKIRL QEGTTNCSGR VEVWHGGSWG TVCDDSWDLD
DAQVVCRQLG CGLALEAGKE AAFGQGTGPI WLNEVKCKGN ESSLWDCPAL SWGHSDCGHK
EDASVKCSEI AKNEGSLNAT GHSSVVALGI LGVILFASLT VLLLWIQKRR QRQRLTVSSR
GENSVHQIQY REMNSCLKAD DLDLQNSSGD HSEVQ
//
