ID   A0A383Z8N7_BALAS        Unreviewed;       795 AA.
AC   A0A383Z8N7;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
GN   Name=ANO9 {ECO:0000313|RefSeq:XP_007171264.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007171264.1};
RN   [1] {ECO:0000313|RefSeq:XP_007171264.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007171264.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU280814}.
CC   -!- SIMILARITY: Belongs to the anoctamin family.
CC       {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU280814}.
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DR   RefSeq; XP_007171264.1; XM_007171202.1.
DR   AlphaFoldDB; A0A383Z8N7; -.
DR   GeneID; 103007922; -.
DR   CTD; 338440; -.
DR   OrthoDB; 534027at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR032394; Anoct_dimer.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF37; ANOCTAMIN-9; 1.
DR   Pfam; PF16178; Anoct_dimer; 1.
DR   Pfam; PF04547; Anoctamin; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU280814};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU280814}.
FT   TRANSMEM        246..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        310..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        352..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        420..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        536..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   TRANSMEM        586..610
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU280814"
FT   DOMAIN          141..200
FT                   /note="Anoctamin dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16178"
FT   DOMAIN          237..728
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          735..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  90230 MW;  696D932D5779AA72 CRC64;
     MRVSPLRGHA HPDGVRAEAP PAGPAPHLGE ESLRILVGTE GDSLLLMDIN TTETEASEPW
     DYVLVADRCT QRNPRQVQRQ QQFLEELERK GFCYKAREDQ EKVFFGIRAD NRVFDRYRRL
     LMEPEATAPR GELAGPTSIP ATTRIRIVNF VLNSKMAAGD TLQDLVKDGV FEAGFPLHKG
     EEDLKKKWAR WRNMFQQQPI GDISREICEA HDVYMCPRGD HNPRYQRLSE TCAFAKLTHL
     FDNEGTVLFA MFMALWATVF LELWKRERAR VVLQWDLYGW DEDQEEMALG LIACPDYQPR
     LHQHSYMRST VILLLSLLMI CLMIGMAHVL VIYRVLAAAL FSSAFPFLGE QVTTAVVVTG
     ALVHYVSILV MTKINKYVAL KLCDFGERRA PLSPSLATGG RIQEKPRTFS ERESKFTIKF
     FTLQFFAHFS SLIYIAFILG RINGNPGKSV RLAGLWKLEE CHLSGCMMDL FVQMAIIMGL
     KQTLSNCMEY LGPWLAHKCR SMRATSQDPE LRHWQRNYRL NPVNTFSLFG EFMEMMIQYG
     FTTVFVAAFP LAPLLALFSN LAEIRLDAIK MVRLQRRLVP RKAKDIGTWL LVLEIIGIVA
     VIANGMVIAF TSEFIPRVVY KYRYGPCRQG AHPAVDCLTG YVNHSLSVFY TKDFQNPVEI
     EGSENVTECR YRDYGAAQNS NFTEQSWFLL AIRLAFLILF EHVALCVKLI AAWFVPDVRQ
     SVKNEVLKKK HQRLGEAGLP GPGVGPGPES RSTRDSGPRA QTWSGPRAGQ EAKTQSCCHH
     HHPPQPWLCV CVGGL
//