ID   A0A383ZAL5_BALAS        Unreviewed;      1612 AA.
AC   A0A383ZAL5;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Ras GTPase-activating-like protein IQGAP3 {ECO:0000313|RefSeq:XP_007171919.1};
GN   Name=IQGAP3 {ECO:0000313|RefSeq:XP_007171919.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007171919.1};
RN   [1] {ECO:0000313|RefSeq:XP_007171919.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007171919.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
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DR   RefSeq; XP_007171919.1; XM_007171857.2.
DR   STRING; 310752.A0A383ZAL5; -.
DR   KEGG; bacu:103001626; -.
DR   CTD; 128239; -.
DR   InParanoid; A0A383ZAL5; -.
DR   OrthoDB; 12619at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0120025; C:plasma membrane bounded cell projection; IEA:UniProt.
DR   CDD; cd12207; RasGAP_IQGAP3; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 1.20.5.190; -; 2.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR000593; RasGAP_C.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR001202; WW_dom.
DR   PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR   PANTHER; PTHR14149:SF10; RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF00612; IQ; 4.
DR   Pfam; PF00616; RasGAP; 1.
DR   Pfam; PF03836; RasGAP_C; 1.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00015; IQ; 4.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF143885; RGC domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS50096; IQ; 4.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
DR   PROSITE; PS01159; WW_DOMAIN_1; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT   DOMAIN          14..129
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          651..678
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          969..1202
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
SQ   SEQUENCE   1612 AA;  183094 MW;  80C4A31990075CC0 CRC64;
     MDEQRRQNVA YEYLCRLEEA KRWMEACLKE ELPSPVELEE SLRNGVLLAK LGHCFAPSVV
     PLKKIYDVEQ LRYQATGLHF RHTDNINFWL SAVAHIGLPS TFFPETTDIY DKKNMPRVVY
     CIHALSLFLF RLGLAPQIHD LYGKVKFTAE ELSNMASELA KYGLQLPAFS KIGGILANEL
     SVDEAAVHAA VLAINEAVER GVVKDTLAAL QNPSALLGNL REPLAAIYQE LLAQAKMEKA
     ANARNRNDGE SQDIYDCYLT QAEIQGNINH VNVHGALEVV DDALERQSPE ALLEALQDPV
     LALQGVRRDF ADWYLEQLSS DREQKAQELG LVELLEKEEV QAGVAAANIK GDQEQAMLQA
     VQRINKAIRR GVAADTVKEL MCPEAQLPPV YPFASAVYQQ ELAVLQRQQQ GELGQEELFV
     AVEMLSAVVL INRALEARDA SSFWSSLVNP ATGLAEVEGE NAQRYFDTLV KLQQVHGMDG
     AFLSWNDLQA TVSQVNARIQ EETNQVLAVS LINEALEQNN PEKTLSSLLL PAAGLDDVSL
     PVAPRYHLLL VAAKKQKAQV TGDPGAVLWL EEIRQEVVRA NQDTNTAQRM ALGVAAINQA
     IKEGKAAQTE RVLRNPSVGL RWVVPDCADG YQRVLEDAMA KKRRPGDTAL WVQHDMKDGT
     AYYFHLQTFQ GTWERPPSCR LNTSHLTREE IQLVVTKITA AHDRQQLWKA NVGFIIRLQA
     RLRGFLVRQK FAERSHFLRT WLPAIIKIQA HWRGYRQRKI YLERLQYLKA NTNAVIKIQA
     WARMWAARRR YRRRLGYFQK NVNSIVKIQA FFRARKARDD YRMLVRAPHP PLSVVCRFAH
     LLNQSHQDFL AEAELLKLQE EVVRKIRSNQ QLEQDLNLMD IKIGLLVKNR ITLQEVVSHC
     KKLTKKNKEQ LSDMMVLDKQ KGLKSLSKEK RQKLEAYQHL FYLLQTQPIY LAKLIFQMPQ
     NKTTKFMESV IFSLYNYASN RREAYLLLQL FKTALQEEIK SKVEQPQDMV TGNPTVVRLV
     VRFYRNGRGQ SALREILGKV IQDVLEDKML SIHTDPVHLY KSWINQTEAQ TGQRSHLPYD
     ITPEQALSHP EVQRRLDISL RNLLAMTDKF LAAIISSVDQ IPYGMRYVAK VLKTTLAEKF
     PDATENEVYK VVGNLLYYRF LNPAVVAPDA FDIVAMAAGG ALATPQRHAL GAVAQLLQHA
     AAGKAFSRES QHLRVLNDYL EETHLKFRRF ICRACHVPEP EERFAMDEYS DMVAVAKPVV
     YITVGELVNT HRLLLEHQDW IAPDHCDPLH ELLEDLGELP TVPDLIGENV AADGNVDLSK
     LEVSLTLTNK FEGLETDADD TNARSLLLST KQMLADIMQV HSGDSLKEIL SLSASREQEA
     AHKRLMCRRQ ACEAQTPESL RRHRSLTAHS LLPLAEKQRR VLRNLRRLEG LGLVSASDSY
     QGLVDELAKD IRNQRRHRQR RKAELVKLQA TFQALSTKTT FYEEQGDYYS QYIRACLDHL
     APSSKSSGKG KKQPSLHYTA AQLLEKGVLV EIEDLPTSHF RNVIFDITPG DEAGKFEVNA
     RFLGVDMERF QLHYQDLLQL QYEGVAVMKL FNKAKVNVNL LIFLLNKKFL RK
//