ID A0A383ZAX5_BALAS Unreviewed; 1097 AA.
AC A0A383ZAX5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Protein transport protein Sec24A isoform X1 {ECO:0000313|RefSeq:XP_007172222.1};
GN Name=SEC24A {ECO:0000313|RefSeq:XP_007172222.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007172222.1};
RN [1] {ECO:0000313|RefSeq:XP_007172222.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007172222.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated
CC vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR RefSeq; XP_007172222.1; XM_007172160.2.
DR AlphaFoldDB; A0A383ZAX5; -.
DR STRING; 310752.A0A383ZAX5; -.
DR GeneID; 102999048; -.
DR KEGG; bacu:102999048; -.
DR CTD; 10802; -.
DR InParanoid; A0A383ZAX5; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR PANTHER; PTHR13803:SF1; PROTEIN TRANSPORT PROTEIN SEC24A; 1.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 2.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 432..468
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 505..743
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 748..832
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 843..943
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 969..1043
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..125
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..225
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1097 AA; 120194 MW; 2A9500FAD6678914 CRC64;
MSQPGIPASG GAPIGLQAQN GAARASGSPY TNGPVQNALM SSQVSVSQGY NSQLPGSYPH
LIPAKTLNPV PGQSNSGGSQ TVSPLSNYQG PGQTVYRPSV ASNPVTPSLR SGPVPQMPLP
TSQNPAATPM PSGSFLPGAN IPPPLNWQYN YSSQTNHCPC ASSQPTMSGN TNLTSPQYVS
SGDTSLQNNF IKSGSAPPLV NPPLPTTFQP GAPLGPPPTG GPPPVRALTP QKSTHRAVPQ
PTFNSASNQE GIIPNTNNGS MVVHNSYDEI EGGGFLATPQ LTNKNPTMSR SVGYSYPSLP
PGYQNAIPPS TTRMPPSSLN YPSGPQAFTQ TPLGANHLPA SMSGLSLHPE GLRVINLLQE
RNMLPLTPLQ PPVPNLHEDI QKLNCNPELF RCTLTSIPQT QALLNKAKLP LGLLLHPFKD
LVQLPVVTSS TIVRCRSCRT YINPFVSFLD QRRWKCNLCY RVNDVPEEFM YNPLTRVYGE
PHRRPEVQNA TIEFMAPSEY MLRPPQPPVY LFVFDVSHNA VETGYLNSVC QGLLDNLDLL
PGNTRTKIGF ITFDSTIHFY SLQEGLSQPQ MLIVSDIEDV FIPMPENLLV NLNESKELVQ
DLLKTLPQMF TKTLETQSAL GPALQAAFKL MSPTGGRMSV FQTQLPTLGV GALKPREEPN
QRSSAKEIHL TPSTDFYKKL ALDCSGQQVA VDLFLLSGQY SDLASLGCIS RYSAGSVYYY
PSYHHQHNPV QVQKLQKELQ RYLTRKIGFE AVMRIRCTKG LSIHTFHGNF FVRSTDLLSL
PNVNPDAGYA VQMSVEESLT DTQLVSFQSA LLYTSSKGER RIRVHTLCLP VVSTLNEVFL
GADVQAISGL LANMAVDRSV TASLSDARDA LVNAVIDSLS AYRSSVLSNQ QHGLMVPFSL
RLFPLFVLAL LKQKSFQTGT NACLDERIFA MCQVKNQPLV YLMLTTHPSL YRVDNLSDEG
AVNINDRTIP QPPILQLSVE KLSRDGAFLM DAGSVLMLWV GRNCGQNFLS QVLGVENYAL
IPPTMTDLPE LDTPESARTI AFISWLREQR PFYPILYVIR DESPMKANFL QNMVEDRTES
ALSYYEFLLH IQQQVNK
//
