ID A0A383ZFV4_BALAS Unreviewed; 597 AA.
AC A0A383ZFV4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Autophagy-related protein 16-2 isoform X3 {ECO:0000313|RefSeq:XP_007173754.1};
GN Name=ATG16L2 {ECO:0000313|RefSeq:XP_007173754.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007173754.1};
RN [1] {ECO:0000313|RefSeq:XP_007173754.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007173754.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007173754.1; XM_007173692.1.
DR AlphaFoldDB; A0A383ZFV4; -.
DR GeneID; 103003557; -.
DR CTD; 89849; -.
DR OrthoDB; 458014at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF7; PROTEIN ATG16L2; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 17..208
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 310..351
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 354..395
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 396..437
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 534..563
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 119..222
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 597 AA; 66249 MW; C7EA04BB1DE373C0 CRC64;
MAGPSDPGVP AARWKRHIVR QLRQRDRTQK ALFLELVPAY NRLIEKAELL AQFSEKLQPE
PTHVTRALLQ GPWEEESGPD SDRVPSPAAL RVKWQEEEEG LRLVCGEMAY QVVEKSAALG
TLESQLEERQ SRLAALEARV AQLQEAREKE AGQVGARRAL NAAQRAAYEA LRVHVGHQEA
ALRRLEEEAR DLLDRLVRRK ARAAAERNLR NERRERAKQA RVSQELKKAA KRTVSISESP
DTLGDGIREE ADTLALAAEP LESEDGEKWK RPFSFKKRRG HSIGGAPEQR YQSIPVCVAA
RLPTRAQDVL DAHLSEVNAV RFGPSSSLLA TGGADRLILL WNVVGGRLEA NQTLEGAGGS
ITSVDFDPSG SQVLAATYNK AAQLWKVGEA QSKETLSGHT DKVTAAKFKL TRHQAVTGSR
DRTVKEWDLG RAYCSRTINV LSYCNDVVCG DHVIISGHND QKIRFWDSRG PRCTQVIPVQ
GRVTSLSLSH DQLHLLSCSR DDTLKVIDLR VSNIRQVFRA DGFRCGSDWT KAVFSPDRSY
ALAGSWDGAL YIWDVDTGKL ESSLRGPHCA AVNAVAWCYS GSHVVSVDQA RKVVLWH
//
