ID A0A383ZKM2_BALAS Unreviewed; 325 AA.
AC A0A383ZKM2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 03-MAY-2023, entry version 15.
DE SubName: Full=Vesicle-trafficking protein SEC22a isoform X3 {ECO:0000313|RefSeq:XP_007175695.1};
GN Name=SEC22A {ECO:0000313|RefSeq:XP_007175695.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007175695.1};
RN [1] {ECO:0000313|RefSeq:XP_007175695.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007175695.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in vesicle transport between the ER and the
CC Golgi complex. {ECO:0000256|ARBA:ARBA00003595}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR RefSeq; XP_007175695.1; XM_007175633.1.
DR AlphaFoldDB; A0A383ZKM2; -.
DR GeneID; 103005710; -.
DR CTD; 26984; -.
DR OrthoDB; 129635at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR043546; Sec22a/c.
DR PANTHER; PTHR46258; LONGIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46258:SF3; VESICLE-TRAFFICKING PROTEIN SEC22A; 1.
DR Pfam; PF13774; Longin; 1.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..325
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016846686"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..159
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
SQ SEQUENCE 325 AA; 37214 MW; 1708448DAF95742B CRC64;
MYLYVGFCLL LFERLPSWNL EPTVITPQGS EEDRSSLSVE MSMILSASVI RVRDGLPLSA
STDYEQGTGM QECRKYFKKL SRKLAQLPDR CTLKTGHYNI NFISSMGVSY MMLCTENYPN
VLAFSFLDEL QKEFITTYNM MKTNTAVRPY CFIEFDNFIQ RTKQRYNNPR SLSTKINLSD
MQMEIKLRPP YQISMGELGS ANGVTSAFSV DYKGAGKISS AHQRLEPATL SGIVAFILSL
LCAALNLIRG FHAIESLLQC YLFVYYTGWR NVKSFLTFGL ICLCNMYLYE LRNLWQLFFH
VTVGAFVTLQ IWLRQAQGKA PDYDV
//
