ID A0A383ZR00_BALAS Unreviewed; 615 AA.
AC A0A383ZR00;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=LOW QUALITY PROTEIN: protein CBFA2T1 {ECO:0000313|RefSeq:XP_007177552.1};
GN Name=RUNX1T1 {ECO:0000313|RefSeq:XP_007177552.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007177552.1};
RN [1] {ECO:0000313|RefSeq:XP_007177552.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007177552.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CBFA2T family.
CC {ECO:0000256|ARBA:ARBA00011004}.
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DR RefSeq; XP_007177552.1; XM_007177490.2.
DR AlphaFoldDB; A0A383ZR00; -.
DR STRING; 310752.A0A383ZR00; -.
DR GeneID; 103005533; -.
DR KEGG; bacu:103005533; -.
DR CTD; 862; -.
DR InParanoid; A0A383ZR00; -.
DR OrthoDB; 5314634at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.10.250.230; -; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR013290; CBFA2T1.
DR InterPro; IPR013289; CBFA2T1/2/3.
DR InterPro; IPR014896; NHR2.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR PANTHER; PTHR10379:SF5; PROTEIN CBFA2T1; 1.
DR Pfam; PF08788; NHR2; 1.
DR Pfam; PF07531; TAFH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR01875; ETOFAMILY.
DR PRINTS; PR01876; MTG8PROTEIN.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 131..226
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT DOMAIN 526..562
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 36..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 465..512
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 76..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 68718 MW; 3DF6C3BD814BBDA5 CRC64;
MCHPDKPFTS DKLRCVFNEY KAAVWVPPRL RPLSCAPLPE DRTEKHSTMP DSPVDVKTPS
RLTPPTMPPP PTTQGAPRTS SFTPTTLTNG TSHSPTALNG APSPPNGFSN GPSSSSSSSL
ANQQLPPACG ARQLSKLKRF LTTLQQFGND ISPEIGERVR TLVLGLVNST LTIEEFHSKL
QEATNFPLRP FVIPFLKANL PLLQRELLHC ARLAKQNPAQ YLAQHEQLLL DASTTSPVDS
SELLLDVNEN GKRRTPDRTK ENGFDREPLH SEHPSKRPCT ISPGQRYSPN NGLSYQPNGL
PHPTPPPPQH YRLDDMAIAH HYRDSYRHPS HRDLRDRNRP MGLHGTRQEE MIDHRLTDRE
WAEEWKHLDH LLNCIMDMVE KTRRSLTVLR RCQEADREEL NYWIRRYSDA EDLKKGGSGS
SSHSRQQSPV NPDPVALDAH REFLHRPASG YVPEEIWKKA EEAVNEVKRQ AMTELQKAVS
EAERKAHDMI TSERAKMERT VAEAKRQAAE DALAVINQQE DSSESCWNCG RKASETCSGC
NTARYCGSFC QHKDWEKHHH ICGQTLQAQQ QGDTPAVSSS VTPNSGAGSP MDTPPAATPR
STTPGTPSTI ETTPR
//
