ID A0A383ZU60_BALAS Unreviewed; 322 AA.
AC A0A383ZU60;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
GN Name=ATP1B4 {ECO:0000313|RefSeq:XP_007178665.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007178665.1};
RN [1] {ECO:0000313|RefSeq:XP_007178665.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007178665.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- FUNCTION: May act as a transcriptional coregulator during muscle
CC development through its interaction with SNW1. Has lost its ancestral
CC function as a Na,K-ATPase beta-subunit.
CC {ECO:0000256|ARBA:ARBA00037398}.
CC -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC which catalyzes the hydrolysis of ATP coupled with the exchange of
CC Na(+) and K(+) ions across the plasma membrane.
CC {ECO:0000256|RuleBase:RU362099}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. Nucleus
CC inner membrane {ECO:0000256|ARBA:ARBA00037816}; Single-pass type II
CC membrane protein {ECO:0000256|ARBA:ARBA00037816}.
CC -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC {ECO:0000256|ARBA:ARBA00005876, ECO:0000256|RuleBase:RU362099}.
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DR RefSeq; XP_007178665.1; XM_007178603.2.
DR AlphaFoldDB; A0A383ZU60; -.
DR GeneID; 103001473; -.
DR CTD; 23439; -.
DR OrthoDB; 2880589at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1660; Na, k-atpase alpha subunit; 1.
DR InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR NCBIfam; TIGR01107; Na_K_ATPase_bet; 1.
DR PANTHER; PTHR11523:SF12; PROTEIN ATP1B4; 1.
DR PANTHER; PTHR11523; SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT; 1.
DR Pfam; PF00287; Na_K-ATPase; 2.
DR PROSITE; PS00390; ATPASE_NA_K_BETA_1; 1.
DR PROSITE; PS00391; ATPASE_NA_K_BETA_2; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362099};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362099};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362099};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362099}; Transport {ECO:0000256|RuleBase:RU362099}.
FT TRANSMEM 109..135
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362099"
FT REGION 32..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..73
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 37709 MW; D83DA8D1FC675B6D CRC64;
MRRQLRSRRA PAFPYGYRYR LDDQDEVNQN YLADEEEEAE EEARVMVVPD LEEEEEEEEE
EEKEEEEKEE EESQTQETGS AWWRKWQIVN EYLWDPEKRM SLARTGQSWS LILVIYFFFY
ASLAAVITLC MYTLFLTISP YMPTFTERVK PPGYNDSLQE EMNVDCPPGQ YFIQDGDEDE
DKKACQFKRS FLKNCSGLED PTFGYSTGQP CILLKMNRIV GFRPEPGDPV KVSCKVQRGD
ENDIRSINYY PESASFDLRY YPYYGKLTHV NYTSPLVAMH FTDVVKNQAV PVQCQLKGKG
IINDVINDRF VGRVIFTLNI ET
//
