ID A0A384A1S1_BALAS Unreviewed; 275 AA.
AC A0A384A1S1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform X1 {ECO:0000313|RefSeq:XP_007181288.1};
GN Name=PTPMT1 {ECO:0000313|RefSeq:XP_007181288.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007181288.1};
RN [1] {ECO:0000313|RefSeq:XP_007181288.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007181288.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
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DR RefSeq; XP_007181288.1; XM_007181226.2.
DR AlphaFoldDB; A0A384A1S1; -.
DR STRING; 310752.A0A384A1S1; -.
DR GeneID; 103002568; -.
DR KEGG; bacu:103002568; -.
DR CTD; 114971; -.
DR InParanoid; A0A384A1S1; -.
DR OrthoDB; 1046951at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0008962; F:phosphatidylglycerophosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd14524; PTPMT1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR042165; PTPMT1.
DR InterPro; IPR044596; PTPMT1-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46712; PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1; 1.
DR PANTHER; PTHR46712:SF1; PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 111..262
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 183..251
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 30112 MW; 00E716E0C638B0FF CRC64;
MVPVPLGPGS PEVSLGAGPE VSALRRPAPA VSPSLEAADD SQSSASSLFW PSSRPPPASP
GVGRSSLRPA GWGRMAAGTL LEAGLARVLF YPTLLYTLFR GKMPGPAHRD WYNRIDNTVL
LGALPLRNMT RRLVQDENVR GLITMNEEYE TRFLCNSPKE WKNVGVEQLR LSTIDMTGVP
TLANLQKGVQ FALKYQSLGQ SVYVHCKAGR SRSATMVAAY LIQVYNWTPE EAVRAITKIR
SHIYIRPGQL EVLKEFHKVI TAGAAKNETC HTSQT
//
