ID A0A384A285_BALAS Unreviewed; 450 AA.
AC A0A384A285;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
GN Name=TTYH1 {ECO:0000313|RefSeq:XP_007181451.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007181451.1};
RN [1] {ECO:0000313|RefSeq:XP_007181451.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007181451.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- FUNCTION: Probable chloride channel. May be involved in cell adhesion.
CC {ECO:0000256|ARBA:ARBA00037608}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361114};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU361114}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tweety family.
CC {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007181451.1; XM_007181389.2.
DR AlphaFoldDB; A0A384A285; -.
DR GeneID; 103013361; -.
DR CTD; 57348; -.
DR OrthoDB; 5393599at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd07912; Tweety_N; 1.
DR InterPro; IPR006990; Tweety.
DR PANTHER; PTHR12424:SF5; PROTEIN TWEETY HOMOLOG 1; 1.
DR PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR Pfam; PF04906; Tweety; 1.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361114};
KW Chloride channel {ECO:0000256|RuleBase:RU361114};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|RuleBase:RU361114};
KW Ion transport {ECO:0000256|RuleBase:RU361114};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361114};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361114};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT TRANSMEM 43..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 392..413
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT REGION 428..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 49023 MW; 72EDB0D1BF442327 CRC64;
MGAPPGYRPS AWVHLLHQLP RADFQLRPVP SGFAPQEQEY QQALLLVVAL AGLGLGLSLI
FIAVYLIRFC CCRPPEPPGA KSPPPGGGCV TWSCIAALLV GCAGIGIGFY GNSETSDGVS
QLSSALLHAN HTLTAIDHLV LEMVERLEEA VRTELTTLEE VLTQRTELVA ATRGARRQAE
AVAQQLQGLA FWQGVPLSPL QVAEDVSFVE EERWLAYVLL LLLELLVCLF TLLGLAKQSK
WLVIVMTVVS LLVLVLSWGS MGLEAAAAVG LSDFCSSPDT YILNLTREET GLGSDILSYY
FLCNQAVSNP FQQRLTLSQR ALANIHSQLQ GLEREAVPQF PSAQKLLLSL EETLNVTEGN
FHQLVALLHC RGLHKDYGAA LRGLCEDALE GLLFLLLFSL LSAGALATAL CSLPRAWALF
PPSDDYDDTD DDDPFNPQES KRFVQWQSSI
//
